Author | Silva, Moacir Paranhos | |
Author | Freitas, Luiz Antonio Rodrigues de | |
Author | dosSantos, Washington Luis Conrado | |
Author | Grimaldi Junior, Gabriel | |
Author | Pontes-de-Carvalho, Lain Carlos | |
Author | Santos, Antonio J. Oliveira dos | |
Access date | 2018-07-05T18:36:21Z | |
Available date | 2018-07-05T18:36:21Z | |
Document date | 1996 | |
Citation | SILVA, M. P. et al. A cross-sectional serodiagnostic survey of canine Leishmaniasis due to Leishmania Chagasi. American Journal of Tropical Medicine and Hygiene, v. 55, n. 1, p. 39-44, 1966. | pt_BR |
ISSN | 0002-9637 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/27332 | |
Sponsorship | Brazilian Research Council (CNPq) and the Oswaldo Cruz Foundation (PAPES/FIOCRUZ). Antonio J. Oliveira-dos-Santos and Washington C. Santos received fellowships from the CNPq. | pt_BR |
Language | eng | pt_BR |
Publisher | American Society of Tropical Medicine and Hygiene | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Leishmania Chagasi | pt_BR |
Subject in Portuguese | Leishmaniose visceral | pt_BR |
Subject in Portuguese | Ensaio imunoenzimático | pt_BR |
Subject in Portuguese | Soroprevalência | pt_BR |
Subject in Portuguese | Brasil | pt_BR |
Title | A cross-sectional serodiagnostic survey of canine Leishmaniasis due to Leishmania Chagasi | pt_BR |
Type | Article | pt_BR |
Abstract | Jequie, a community of about 144,500 inhabitants located in the State of Bahia, Brazil, is endemic for
both visceral and cutaneous leishmaniases. In the present epidemiologic study, the urban and inhabited periurban
areas of the town were divided into 140 clusters of0.25 km2 each. The seroprevalence of canine Leishmania antibodies
was investigated using an enzyme-linked immunosorbent assay as a screening test since its sensitivity was significantly
higher than that of an indirect immunofluorescence assay. A total of 1,681 dogs was surveyed in 34 randomly sampled
clusters. The overall prevalence of Leishmania antibodies in the dog population was 23.5%, with intracluster prevalences
ranging from 0% to 67%. There was no correlation of these seroprevalences with the intracluster densities of
canine populations, or with the distances from individual clusters to the town center. Moreover, the Leishmania
transmission did not seem to follow any clear-cut spatial pattern, since large disparities in the seroprevalences of
contiguous clusters were Curiously, human cases of visceral leishmaniasis have never been observed in some
clusters with a relatively high prevalence of canine seroprevalences. Eight parasite isolates from seropositive dogs
were found to belong to the same serodeme and zymodeme as Leishmania (L.) chagasi. The implications of these
findings with respect to the epidemiology and control of American visceral leishmaniasis are discussed | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Osvaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | University of Innsbruck. Institute for General and Experimental Pathology. Medical School. Innsbruck, Austria | pt_BR |
Subject | Leishmania Chagasi | pt_BR |
Subject | Visceral leishmaniases | pt_BR |
Subject | Enzyme immunoassay | pt_BR |
Subject | Seroprevalence | pt_BR |
Subject | Brazil | pt_BR |