Author | Joffe, Luna S. | |
Author | Nimrichter, Leonardo | |
Author | Rodrigues, Marcio Lourenço | |
Author | Del Poeta, Maurizio | |
Access date | 2018-07-26T17:25:45Z | |
Available date | 2018-07-26T17:25:45Z | |
Document date | 2016 | |
Citation | JOFFE, L. S. et al. Potential roles of fungal extracellular vesicles during infection. mSphere, v. 1, n. 4, p. 1-10, 2016. | pt_BR |
ISSN | 2379-5042 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/27679 | |
Language | eng | pt_BR |
Publisher | American Society for Microbiology | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Vesículas extracelulares | pt_BR |
Subject in Portuguese | Fungo | pt_BR |
Title | Potential Roles of Fungal Extracellular Vesicles during Infection | pt_BR |
Type | Article | pt_BR |
DOI | 10.1128/mSphere.00099-16 | |
Abstract | Extracellular vesicles (EVs) are produced by virtually all cell types. Within the past few years, work in this field has revealed more information about fungal EVs. Fungal EVs have been shown to carry proteins, lipids, pigments, polysaccharides, and RNA; these components are known virulence factors, a fact which supports the hypothesis that fungal EVs concentrate pathogenic determinants. Additionally, recent studies have demonstrated that fungal EVs stimulate the host immune system. In this review, putative roles of fungal EVs are discussed, including their potential as vaccination tools and their possible contribution to pathogenesis in invasive fungal diseases. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Departamento de Microbiologia Geral. Rio de Janeiro, RJ, Brasil / University Stony Brook. Department of Molecular Genetics and Microbiology. Stony Brook, New York, USA. | pt_BR |
Affilliation | University Stony Brook. Department of Molecular Genetics and Microbiology. Stony Brook, New York, USA. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | University, Stony Brook. Department of Molecular Genetics and Microbiology. Stony Brook, New York, USA / Veterans Administration Medical Center. Northport, NY, USA. | pt_BR |
Subject | Cryptococcus | pt_BR |