| Author | Lackenby, Angie | |
| Author | Democratis, Jane | |
| Author | Siqueira, Marilda Agudo Mendonça Teixeira de | |
| Author | Zambom, Maria C, | |
| Access date | 2018-07-30T13:05:43Z | |
| Available date | 2018-07-30T13:05:43Z | |
| Document date | 2008 | |
| Citation | LACKENBY, Angie; et al. Rapid quantitation of neuramidinase inhibitor drug resistance in influzenza virus quasispecies. Antiviral Therapy, v. 13, p. 809-820, 2008. | pt_BR |
| ISSN | 1359-6535 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/27698 | |
| Language | eng | pt_BR |
| Publisher | International Medical Press | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Vírus Influenza | pt_BR |
| Subject in Portuguese | inibidor de neuramidinase | pt_BR |
| Subject in Portuguese | Resistência a medicamentos | pt_BR |
| Title | Rapid quantification of neuraminidase inhibitor drug resistance in influenza virus quasispecies | pt_BR |
| Type | Article | |
| Abstract | BACKGROUND:
Emerging resistance of influenza viruses to neuraminidase inhibitors is a concern, both in surveillance of global circulating strains and in treatment of individual patients. Current methodologies to detect resistance rely on the use of cultured virus, thus taking time to complete or lacking the sensitivity to detect mutations in viral quasispecies. Methodology for rapid detection of clinically meaningful resistance is needed to assist individual patient management and to track the transmission of resistant viruses in the community. | pt_BR |
| Affilliation | Health Protection Agency. Centre for Infection. London, UK. | pt_BR |
| Affilliation | Health Protection Agency. Centre for Infection. London, UK / University Hospitals Leicester NHS Trust. Leicester Royal Infirmary. Department of Infection and Tropical Medicine. Leicester, UK. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Health Protection Agency. Centre for Infection. London, UK. | pt_BR |
| Subject | Influenza virus | pt_BR |
| Subject | Neuramidinase inhibitor | pt_BR |
| Subject | drug resistance | pt_BR |
| e-ISSN | 2040-2058 | |
| Embargo date | 2030-01-01 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
