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AutorMatos, Márcia A. D.
AutorReis, Nádia Rúbia S.
AutorKozlowski, Aline G.
AutorTeles, Sheila A.
AutorCastro, Ana Rita C. Motta
AutorMello, Francisco C. A.
AutorGomes, Selma A.
AutorMartins, Regina M. B.
Fecha de acceso2018-07-30T17:57:53Z
Fecha de disponibilización2018-07-30T17:57:53Z
Fecha de publicación2009
ReferenciaMATOS, Márcia A. D. et al. Epidemiological study of hepatitis A, B and C in the largest Afro-Brazilian isolated community. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 103, p.899-905, 2009.pt_BR
ISSN0035-9203pt_BR
URIhttps://www.arca.fiocruz.br/handle/icict/27722
Idiomaengpt_BR
EditorElsevierpt_BR
Derechos de autorrestricted access
Palabras clave en PortuguésVírus da Hepatite Bpt_BR
Palabras clave en PortuguésVírus da Hepatite Apt_BR
Palabras clave en PortuguésVírus da Hepatite Cpt_BR
Palabras clave en PortuguésPrevalênciapt_BR
Palabras clave en Portuguésgenótipospt_BR
Palabras clave en PortuguésBrasilpt_BR
TítuloEpidemiological study of hepatitis A, B and C in the largest Afro-Brazilian isolated communitypt_BR
Tipo del documentoArticle
DOI10.1016/j.trstmh.2009.01.013
Resumen en InglésThis study was conducted to estimate the prevalence and molecular epidemiological features of viral hepatitis A, B and C in the Kalunga population, which represents the largest Afro-Brazilian isolated community. Among 878 individuals studied, the overall prevalence of anti-hepatitis A virus antibodies was 80.9%, with a significant rise from 44.8% to near 100% between the first and fourth decade of life. Rates for hepatitis B surface antigen (HBsAg) and antibody to hepatitis B core antigen (anti-HBc) of 1.8% and 35.4%, respectively, were found. Increasing age, male gender, illiteracy and history of multiple sexual partners were associated with hepatitis B virus (HBV) infection. An occult HBV infection rate of 1.7% (5/295) was found among anti-HBc-positive individuals. HBV genotype A (subtype Aa) was dominant in this community. Only 5/878 individuals (0.6%) were positive for anti-hepatitis C virus (HCV). HCV RNA was detected in three of them, who were infected with genotype 1 (subtype 1a). These findings point out high, intermediate and low endemicity for hepatitis A, B and C, respectively, in the Kalunga community in Brazil. Circulation of HBV genotype A (subtype Aa) in this Afro-Brazilian isolated community indicates the introduction of this virus during the slave trade from Africa to Brazil.pt_BR
AfiliaciónUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.pt_BR
AfiliaciónUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.pt_BR
AfiliaciónUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.pt_BR
AfiliaciónUniversidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, Brasil.pt_BR
AfiliaciónUniversidade Federal de Mato Grosso do Sul. Departamento de Farmácia Bioquímica. Campo Grande, MS, Brasilpt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ. Brasil.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ. Brasil.pt_BR
AfiliaciónUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.pt_BR
Palavras clave en InglêsHepatitis A viruspt_BR
Palavras clave en InglêsHepatitis B viruspt_BR
Palavras clave en InglêsHepatitis C viruspt_BR
Palavras clave en Inglêsprevalencept_BR
Palavras clave en InglêsGenotypept_BR
Palavras clave en InglêsBrazilpt_BR
e-ISSN1878-3503
Fecha de embargo2030-01-01


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