| Author | Andrade, Márcia Cristina Ribeiro | |
| Author | Leite, José Paulo Gagliardi | |
| Author | Cabello, Pedro Hernan | |
| Access date | 2018-08-07T13:05:54Z | |
| Available date | 2018-08-07T13:05:54Z | |
| Document date | 2009 | |
| Citation | ANDRADE, Márcia Cristina Ribeiro; LEITE, José Paulo Gagliardi; CABELLO, Pedro Hernan. Frequency of the major histocompatibility complex Mamu-A*01 allele in a closed breeding colony of rhesus monkey (Macaca mulatta) from Brazil. Med Primatol., v.38, p.39-41, 2009. | pt_BR |
| ISSN | 0047-2565 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/27972 | |
| Language | eng | pt_BR |
| Publisher | Wiley | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Vírus da Imunodeficiência humana | pt_BR |
| Subject in Portuguese | Macacos rhesus | pt_BR |
| Title | Frequency of the major histocompatibility complex Mamu-A*01 allele in a closed breeding colony of rhesus monkey (Macaca mulatta) from Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1111/j.1600-0684.2008.00301.x | |
| Abstract | Rhesus monkeys are relevant models for human diseases. The simian immunodeficiency virus (SIV) infection is an useful macaque model for assessing human immunodeficiency virus (HIV) vaccine strategies. Susceptibility and resistance to viruses have been associated with particular major histocompatibility complex (MHC) molecules. Several epitopes in the HIV structural and non-structural protein restricted by distinct MHC class I haplotypes are important targets for human cytotoxic T lymphocytes, which mediate protection against SIVmac infection. Mamu-A*01, for example, is a MHC class I molecule of rhesus monkeys that presents a peptide from SIV gag protein. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz.. Departamento de Primatologia. Centro de Criação de Animais de Laboratório. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparadal. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Humana. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | human immunodeficiency virus | pt_BR |
| Subject | Mamu-A*01 | pt_BR |
| Subject | rhesus macaques | pt_BR |
| e-ISSN | 1600-0684 | |
| Embargo date | 2030-01-01 | |
