| Author | Rodrigues, Priscila Thiara | |
| Author | Valdivia, Hugo O. | |
| Author | Santos, Thais Teodoro de Oliveira | |
| Author | Alves, João Marcelo P | |
| Author | Duarte, Ana Maria R. C. | |
| Author | Cerutti Junior, Crispim | |
| Author | Buery, Julyana Cerqueira | |
| Author | Brito, Cristiana Ferreira Alves de | |
| Author | Souza Júnior, Júlio César de | |
| Author | Hirano, Zelinda Maria Braga | |
| Author | Bueno, Marina G. | |
| Author | Dias, José Luiz Catão | |
| Author | Malafronte, Rosely S. | |
| Author | Andrade, Simone Ladeia | |
| Author | Mita, Toshihiro | |
| Author | Santamaria, Ana Maria | |
| Author | Calzada, José E. | |
| Author | Tantular, Indah S. | |
| Author | Kawamoto, Fumihiko | |
| Author | Raijmakers, Leonie R. J. | |
| Author | Mueller, Ivo | |
| Author | Pacheco, M. Andreina | |
| Author | Escalante, Ananias A. | |
| Author | Felger, Ingrid | |
| Author | Ferreira, Marcelo U. | |
| Access date | 2018-09-21T17:20:46Z | |
| Available date | 2018-09-21T17:20:46Z | |
| Document date | 2018 | |
| Citation | RODRIGUES, Priscila Thiara et al. Human migration and the spread of malaria parasites to the New World. Sci Rep., v. 8, n. 1, 1993, 2018 | pt_BR |
| ISSN | 2045-2322 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/28969 | |
| Language | eng | pt_BR |
| Publisher | Nature Publishing Group | pt_BR |
| Rights | restricted access | pt_BR |
| Subject in Portuguese | Plasmodium falciparum | pt_BR |
| Subject in Portuguese | Malaria | pt_BR |
| Title | Human migration and the spread of malaria parasites to the New World | pt_BR |
| Type | Article | |
| DOI | 10.1038/s41598-018-19554-0 | |
| Abstract | We examined the mitogenomes of a large global collection of human malaria parasites to explore how and when Plasmodium falciparum and P. vivax entered the Americas. We found evidence of a significant contribution of African and South Asian lineages to present-day New World malaria parasites with additional P. vivax lineages appearing to originate from Melanesia that were putatively carried by the Australasian peoples who contributed genes to Native Americans. Importantly, mitochondrial lineages of the P. vivax-like species P. simium are shared by platyrrhine monkeys and humans in the Atlantic Forest ecosystem, but not across the Amazon, which most likely resulted from one or a few recent human-to-monkey transfers. While enslaved Africans were likely the main carriers of P. falciparum mitochondrial lineages into the Americas after the conquest, additional parasites carried by Australasian peoples in pre-Columbian times may have contributed to the extensive diversity of extant local populations of P. vivax. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciencias Biomedicas. Departamento de Parasitologia. São Paulo, SP, Brazil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Biologicas. Laboratorio de Imunologia e Genomica Parasitaria. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciencias Biomedicas. Departamento de Parasitologia. São Paulo, SP, Brazil | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciencias Biomedicas. Departamento de Parasitologia. São Paulo, SP, Brazil | pt_BR |
| Affilliation | Estado de São Paulo. Secretaria de Saude. Superintendencia de controle de Endemias. Laboratorio de Bioquimica e Biologia Molecular. São Paulo, SP, Brazil | pt_BR |
| Affilliation | Universidade Federal do Espírito Santo. Departamento de Medicina Social. Vitória, ES, Brazil | pt_BR |
| Affilliation | Universidade Federal do Espírito Santo. Departamento de Medicina Social. Vitória, ES, Brazil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Laboratorio de Malaria. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Universidade Regional de Blumenau. Blumenau, SC, Brazil/Centro de Pesquisa Biológica de Indaial. Indaial, SC, Brazil | pt_BR |
| Affilliation | Universidade Regional de Blumenau. Blumenau, SC, Brazil/Centro de Pesquisa Biológica de Indaial. Indaial, SC, Brazil | pt_BR |
| Affilliation | Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia.Departamento de Patologia. São Paulo, SP, Brazil | pt_BR |
| Affilliation | Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia.Departamento de Patologia. São Paulo, SP, Brazil | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo. Laboratorio de Protozoologia. São Paulo, MG, Brazil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Doenças Parasitárias. Rio de Janeiro, RJ, Brazil | pt_BR |
| Affilliation | Department of Tropical Medicine and Parasitology. Juntendo University School of Medicine. Tokyo, Japan | pt_BR |
| Affilliation | Department of Parasitology. Gorgas Memorial Institute of Health. Panama City. Panama | pt_BR |
| Affilliation | Department of Parasitology. Gorgas Memorial Institute of Health. Panama City. Panama | pt_BR |
| Affilliation | Department of Parasitology. Faculty of Medicine. and Institute of Tropical Disease. Airlangga University. Surabaya, Indonesia | pt_BR |
| Affilliation | Department of Social and Environmental Medicine. Institute of Scientific Research. Oita University. Oita, Japan | pt_BR |
| Affilliation | Research Laboratory for Archaeology and the History of Art. University of Oxford. Oxford, United Kingdom | pt_BR |
| Affilliation | Division of Population Health and Immunity. Walter and Eliza Hall Institute. Parkville, Victoria Australia/Department of Parasites and Insect Vectors. Institut Pasteur. Paris, France | pt_BR |
| Affilliation | Department of Biology. Institute for Genomics and Evolutionary Medicine. Temple University. Philadelphia, PA, United States of America | pt_BR |
| Affilliation | Department of Biology. Institute for Genomics and Evolutionary Medicine. Temple University. Philadelphia, PA, United States of America | pt_BR |
| Affilliation | Swiss Tropical and Public Health Institute. Basel, Switzerland/University of Basel. Basel, Switzerland | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciencias Biomedicas. Departamento de Parasitologia. São Paulo, SP, Brazil | pt_BR |
| Subject | Plasmodium falciparum | pt_BR |
| Subject | Malaria | pt_BR |
| Embargo date | 2022-01-01 | |
