Author | Silva, Gulnar Azevedo e | |
Author | Moura, Lenildo | |
Author | Curado, Maria Paula | |
Author | Gomes, Fabio da Silva | |
Author | Otero, Ubirani | |
Author | Rezende, Leandro Fórnias Machado | |
Author | Daumas, Regina Paiva | |
Author | Guimarães, Raphael Mendonça | |
Author | Meira, Karina Cardoso | |
Author | Leite, Iuri da Costa | |
Author | Valente, Joaquim Gonçalves | |
Author | Moreira, Ronaldo Ismério | |
Author | Koifman, Rosalina | |
Author | Malta, Deborah Carvalho | |
Author | Mello, Marcia Sarpa de Campos | |
Author | Guedes, Thiago Wagnos Guimarães | |
Author | Boffetta, Paolo | |
Access date | 2018-10-04T14:02:13Z | |
Available date | 2018-10-04T14:02:13Z | |
Document date | 2016 | |
Citation | AZEVEDO E SILVA, Gulnar. et al. The fraction of cancer attributable to ways of life, infections, occupation, and environmental agents in Brazil in 2020. PLoS ONE, v. 11, n. 2, p. e0148761, 2016 | pt_BR |
ISSN | 1932-6203 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/29335 | |
Language | eng | pt_BR |
Rights | open access | pt_BR |
Title | The Fraction of Cancer Attributable to Ways of Life, Infections, Occupation, and Environmental Agents in Brazil in 2020 | pt_BR |
Type | Article | pt_BR |
DOI | 10.1371/journal.pone.0148761 | |
Abstract | Many human cancers develop as a result of exposure to risk factors related to the environment and ways of life. The aim of this study was to estimate attributable fractions of 25 types of cancers resulting from exposure to modifiable risk factors in Brazil. The prevalence of exposure to selected risk factors among adults was obtained from population-based surveys conducted from 2000 to 2008. Risk estimates were based on data drawn from meta-analyses or large, high quality studies. Population-attributable fractions (PAF) for a combination of risk factors, as well as the number of preventable deaths and cancer cases, were calculated for 2020. The known preventable risk factors studied will account for 34% of cancer cases among men and 35% among women in 2020, and for 46% and 39% deaths, respectively. The highest attributable fractions were estimated for tobacco smoking, infections, low consumption of fruits and vegetables, excess weight, reproductive factors, and physical inactivity. This is the first study to systematically estimate the fraction of cancer attributable to potentially modifiable risk factors in Brazil. Strategies for primary prevention of tobacco smoking and control of infection and the promotion of a healthy diet and physical activity should be the main priorities in policies for cancer prevention in the country. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro. Instituto de Medicina Social. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Pan-Americana Health Organization. Brasília, DF, Brasil. | pt_BR |
Affilliation | Hospital AC Camargo. AC Camargo Cancer Center. São Paulo, SP, Brasil./ International Prevention Research Institute, Lyon, France. | pt_BR |
Affilliation | Ministério da Saúde. Instituto Nacional do Cancer. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Ministério da Saúde. Instituto Nacional do Cancer. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade de São Paulo. Escola de Medicina. Departamento de Medicina Preventiva. São Paulo, SP, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Politécnica de Saúde Joaquim Venâncio. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal do Rio Grande do Norte. Escola de Enfermagem. Natal, RN, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade de São Paulo. Escola de Medicina. Departamento de Medicina Preventiva. São Paulo, SP, Brasil. | pt_BR |
Affilliation | Ministério da Saúde. Secretaria de Vigilância Sanitária. Brasília, DF, Brasil. | pt_BR |
Affilliation | Ministério da Saúde. Instituto Nacional do Cancer. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro. Instituto de Medicina Social. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America. | pt_BR |