| Author | Magidson, Jessica F | |
| Author | Li, Xin | |
| Author | Mimiaga, Matthew J | |
| Author | Moore, Ayana T | |
| Author | Srithanaviboonchai, Kriengkrai | |
| Author | Friedman, Ruth Khalili | |
| Author | Limbada, Mohammad | |
| Author | Hughes, James P | |
| Author | Cummings, Vanessa | |
| Author | Gaydos, Charlotte A | |
| Author | Elharrar, Vanessa | |
| Author | Celentano, David | |
| Author | Mayer, Kenneth H | |
| Author | Safren, Steven A | |
| Access date | 2018-10-08T15:25:31Z | |
| Available date | 2018-10-08T15:25:31Z | |
| Document date | 2016 | |
| Citation | MAGIDSON, J. F. et al. Antiretroviral Medication Adherence and Amplified HIV Transmission Risk Among Sexually Active HIV-Infected Individuals in Three Diverse International Settings. AIDS and behavior, v. 20, n. 4, p. 699–709, 2016 | pt_BR |
| ISSN | 1090-7165 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/29427 | |
| Language | eng | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Antiretroviral Medication Adherence and Amplified HIV Transmission Risk Among Sexually Active HIV-Infected Individuals in Three Diverse International Settings | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1007/s10461-015-1142-7 | |
| Abstract | Successful biomedical prevention/treatment-as-prevention (TasP) requires identifying individuals at greatest risk for transmitting HIV, including those with antiretroviral therapy (ART) nonadherence and/or 'amplified HIV transmission risk,' defined as condomless sex with HIV-uninfected/unknown-status partners when infectious (i.e., with detectable viremia or STI diagnosis according to Swiss criteria for infectiousness). This study recruited sexually-active, HIV-infected patients in Brazil, Thailand, and Zambia to examine correlates of ART nonadherence and 'amplified HIV transmission risk'. Lower alcohol use (OR = .71, p < .01) and higher health-related quality of life (OR = 1.10, p < .01) were associated with greater odds of ART adherence over and above region. Of those with viral load data available (in Brazil and Thailand only), 40 % met Swiss criteria for infectiousness, and 29 % had 'amplified HIV transmission risk.' MSM had almost three-fold (OR = 2.89, p < .001) increased odds of 'amplified HIV transmission risk' (vs. heterosexual men) over and above region. TasP efforts should consider psychosocial and contextual needs, particularly among MSM with detectable viremia. | pt_BR |
| Affilliation | Department of Psychiatry. Harvard Medical School/Massachusetts General Hospital. Boston, MA, USA. | pt_BR |
| Affilliation | Fred Hutchinson Cancer Research Center. Seattle, WA, USA. | pt_BR |
| Affilliation | Department of Psychiatry. Harvard Medical School/Massachusetts General Hospital. Boston, MA, USA./ Harvard School of Public Health. Boston, MA, USA./ The Fenway Institute, Fenway Health. Boston, MA, USA. | pt_BR |
| Affilliation | FHI360, Durham, NC, USA. | pt_BR |
| Affilliation | Research Institute for Health Sciences. Chiang Mai University. Chiang Mai, Thailand./ Faculty of Medicine. Chiang Mai Universit., Chiang Mai, Thailand. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Centre for Infectious Disease Research in Zambia. Lusaka, Zambia. | pt_BR |
| Affilliation | Fred Hutchinson Cancer Research Center. Seattle, WA, USA./ University of Washington. Seattle, WA, USA. | pt_BR |
| Affilliation | Division of Infectious Diseases. Departments of Pathology and Medicine. Johns Hopkins School of Medicine. Baltimore, MD, USA. | pt_BR |
| Affilliation | Division of Infectious Diseases. Departments of Pathology and Medicine. Johns Hopkins School of Medicine. Baltimore, MD, USA. | pt_BR |
| Affilliation | National Institute of Allergy and Infectious Disease (NIAID), Bethesda, MD, USA. | pt_BR |
| Affilliation | Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. | pt_BR |
| Affilliation | The Fenway Institute. Fenway Health. Boston, MA, USA./ Harvard Medical School/Beth Israel Deaconess Medical Center. Boston, MA, USA. | pt_BR |
| Affilliation | The Fenway Institute. Fenway Health. Boston, MA, USA./ Department of Psychology. University of Miami. Coral Gables, FL, USA. | pt_BR |
| Subject | Adherence | pt_BR |
| Subject | Treatment as prevention | pt_BR |
| Subject | HIV transmission | pt_BR |
| Subject | Amplified risk | pt_BR |
| Subject | Alcohol use | pt_BR |
| Subject | MSM | pt_BR |
| Subject | Biomedical prevention | pt_BR |
| Embargo date | 2028-08-30 | |
