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GENOME SEQUENCE OF THE HUMAN PATHOGEN VIBRIO CHOLERAE AMAZONIA
Autor
Afiliación
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil.
Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Biologia Marinha. Rio de Janeiro, RJ, Brasil.
Radboud University Nijmegen Medical Centre. Nijmegen Centre for Molecular Life Sciences. Centre for Molecular and Biomolecular Informatics. Nijmegen, Netherlands / San Diego State University. Department of Biology and Department of Computer Science. San Diego, CA, USA.
San Diego State University. Department of Biology and Department of Computer Science. San Diego, CA, USA.
Osaka University. Research Institute for Microbial Diseases. International Research Center for Infectious Diseases. Laboratory of Genomic Research on Pathogenic Bacteria. Osaka, Japan.
Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Biologia Marinha. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil.
Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Biologia Marinha. Rio de Janeiro, RJ, Brasil.
Radboud University Nijmegen Medical Centre. Nijmegen Centre for Molecular Life Sciences. Centre for Molecular and Biomolecular Informatics. Nijmegen, Netherlands / San Diego State University. Department of Biology and Department of Computer Science. San Diego, CA, USA.
San Diego State University. Department of Biology and Department of Computer Science. San Diego, CA, USA.
Osaka University. Research Institute for Microbial Diseases. International Research Center for Infectious Diseases. Laboratory of Genomic Research on Pathogenic Bacteria. Osaka, Japan.
Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Biologia Marinha. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil.
Resumen en ingles
Vibrio cholerae O1 Amazonia is a pathogen that was isolated from cholera-like diarrhea cases in at least two countries, Brazil and Ghana. Based on multilocus sequence analysis, this lineage belongs to a distinct profile compared to strains from El Tor and classical biotypes. The genomic analysis revealed that it contains Vibrio pathogenicity island 2 and a set of genes related to pathogenesis and fitness, such as the type VI secretion system, present in choleragenic V. cholerae strains.
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