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| Autor | Ratcliffe, Norman A. | |
| Autor | Mello, Cicero B. | |
| Autor | Garcia, Eloi S. | |
| Autor | Butt, Tariq M. | |
| Autor | Azambuja, Patricia | |
| Fecha de acceso | 2018-11-27T15:17:39Z | |
| Fecha de disponibilización | 2018-11-27T15:17:39Z | |
| Fecha de publicación | 2011 | |
| Referencia | RATCLIFFE, Norman A. et al. Insect natural products and processes: New treatments for human disease. Insect Biochemistry and Molecular Biology, v.41, p.747-769, 2011. | pt_BR |
| ISSN | 0965-1748 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/30258 | |
| Idioma | eng | pt_BR |
| Editor | Elsevier | pt_BR |
| Derechos de autor | restricted access | |
| Palabras clave en Portugués | Produtos naturais de insetos | pt_BR |
| Palabras clave en Portugués | Medicina Tradicional | pt_BR |
| Palabras clave en Portugués | Mel | pt_BR |
| Palabras clave en Portugués | Medicamentos | pt_BR |
| Palabras clave en Portugués | Veneno | pt_BR |
| Palabras clave en Portugués | Seda | pt_BR |
| Palabras clave en Portugués | Larvas | pt_BR |
| Palabras clave en Portugués | Fatores antimicrobianos | pt_BR |
| Palabras clave en Portugués | Anticoagulantes | pt_BR |
| Palabras clave en Portugués | Agentes anti-câncer | pt_BR |
| Título | Insect natural products and processes: new treatments for human disease | pt_BR |
| Tipo del documento | Article | |
| DOI | 10.1016/j.ibmb.2011.05.007 | |
| Resumen en Inglés | In this overview, some of the more significant recent developments in bioengineering natural products from insects with use or potential use in modern medicine are described, as well as in utilisation of insects as models for studying essential mammalian processes such as immune responses to pathogens. To date, insects have been relatively neglected as sources of modern drugs although they have provided valuable natural products, including honey and silk, for at least 4-7000 years, and have featured in folklore medicine for thousands of years. Particular examples of Insect Folk Medicines will briefly be described which have subsequently led through the application of molecular and bioengineering techniques to the development of bioactive compounds with great potential as pharmaceuticals in modern medicine. Insect products reviewed have been derived from honey, venom, silk, cantharidin, whole insect extracts, maggots, and blood-sucking arthropods. Drug activities detected include powerful antimicrobials against antibiotic-resistant bacteria and HIV, as well as anti-cancer, anti-angiogenesis and anti-coagulant factors and wound healing agents. Finally, the many problems in developing these insect products as human therapeutic drugs are considered and the possible solutions emerging to these problems are described. | pt_BR |
| Afiliación | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica e Fisiologia de Insetos. Rio de Janeiro, RJ. Brasil / Swansea University. College of Science. Department of Biosciences,. Swansea, Wales, UK. | pt_BR |
| Afiliación | Universidade Federal Fluminense. Departamento de Biologia Geral. Laboratório de Biologia de Insetos. Niterói, RJ, Brasil. | pt_BR |
| Afiliación | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica e Fisiologia de Insetos. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Afiliación | Swansea University. College of Science. Department of Biosciences,. Swansea, Wales, UK. | pt_BR |
| Afiliación | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica e Fisiologia de Insetos. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Palavras clave en Inglês | Insect natural products | pt_BR |
| Palavras clave en Inglês | Medicinal drugs | pt_BR |
| Palavras clave en Inglês | Folk medicine | pt_BR |
| Palavras clave en Inglês | Honey | pt_BR |
| Palavras clave en Inglês | Venom | pt_BR |
| Palavras clave en Inglês | Silk | pt_BR |
| Palavras clave en Inglês | Cantharidin | pt_BR |
| Palavras clave en Inglês | Maggots | pt_BR |
| Palavras clave en Inglês | Antimicrobial factors | pt_BR |
| Palavras clave en Inglês | Anticoagulants | pt_BR |
| Palavras clave en Inglês | Anti-cancer agents | pt_BR |
| e-ISSN | 1879-0240 | |
| Fecha de embargo | 2030-01-01 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar |
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