| Author | Macêdo, Auricélio Alves de | |
| Author | Marciano, Ana Paula Vieira | |
| Author | Rocha, Luciana Morais | |
| Author | Alves Júnior, José Roberto Ferreira | |
| Author | Faria, Ana Maria Caetano de | |
| Author | Bittar, Joely Ferreira Figueiredo | |
| Author | Araújo, Márcio Sobreira Silva | |
| Author | Santos, Renato L. | |
| Author | Martins Filho, Olindo Assis | |
| Access date | 2018-11-29T12:59:06Z | |
| Available date | 2018-11-29T12:59:06Z | |
| Document date | 2013 | |
| Citation | MACÊDO, Auricélio Alves de et al. Comparative phenotypic profile of subpopulations of peripheral blood leukocytes in European (Bos taurus taurus) and Zebu cattle (Bos taurus indicus). Genet Mol Res.,v. 12, n. 4, p. 6838-49, 2013 | pt_BR |
| ISSN | 1676-5680 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/30310 | |
| Language | eng | pt_BR |
| Publisher | GMR | pt_BR |
| Rights | restricted access | pt_BR |
| Subject in Portuguese | Bovino | pt_BR |
| Subject in Portuguese | imunidade inata | pt_BR |
| Subject in Portuguese | adaptação da imunidade | pt_BR |
| Subject in Portuguese | leucocitos | pt_BR |
| Subject in Portuguese | citometria de fluxo | pt_BR |
| Title | Comparative phenotypic profile of subpopulations of peripheral blood leukocytes in European (Bos taurus taurus) and Zebu cattle (Bos taurus indicus) | pt_BR |
| Type | Article | |
| DOI | 10.4238/2013 | |
| Abstract | Differences in cellular and humoral immunity in Zebu (Bos taurus indicus) and European (B. taurus taurus) cattle breeds, which may be related to differences in resistance or susceptibility to infectious or parasitic diseases, are largely unknown. This study aimed to perform a comparative analysis of innate and adaptive immunity of European (including Holstein, Brown Swiss, and Hereford) and Zebu (including Gir, Nelore, and Guzera) breeds, by assessing their peripheral blood leukocyte profiles (i.e., monocytes, eosinophils, and lymphocytes, including CD4+ and CD8+ T cells, and CD21+ B cells). Higher frequencies of cells involved in innate immunity were observed in Zebu breeds, particularly monocytes and non-T and non-B cells (13.37 ± 0.9058 and 37.67 ± 1.55, respectively). This finding may contribute to the increased resistance of B. taurus indicus to certain infectious and parasitic diseases. Considering other leukocyte populations in the peripheral blood, among-breed variation was greater than differences between the two subspecies. This study will serve as a basis for further investigations regarding comparative immunology and resistance to infectious and parasitic diseases of cattle. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Clínica e Cirurgia Veterinárias. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Universidade de Uberaba. Uberaba, MG, Brasil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Bioquímica e Imunologia. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Universidade de Uberaba. Uberaba, MG, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Clínica e Cirurgia Veterinárias. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil | pt_BR |
| Subject | Bovine | pt_BR |
| Subject | Innate immunity | pt_BR |
| Subject | Adaptive immunity | pt_BR |
| Subject | Leukocyte | pt_BR |
| Subject | Flow cytometry | pt_BR |
| Embargo date | 2030-01-01 | |
