| Author | Gomes, Marisa Zenaide Ribeiro | |
| Author | Oliveira, Raquel Vasconcellos C. de | |
| Author | Machado, Carolina Romero | |
| Author | Conceição, Magda de Souza da | |
| Author | Souza, Cristina Vieira de | |
| Author | Lourenço, Maria Cristina da Silva | |
| Author | Asensi, Marise Dutra | |
| Access date | 2018-11-29T16:18:12Z | |
| Available date | 2018-11-29T16:18:12Z | |
| Document date | 2012 | |
| Citation | GOMES, Marisa Zenaide Ribeiro et al. Factors associated with epidemic multiresistant Pseudomonas aeruginosa infections in a hospital with AIDS-predominant admissions. Brazilian Journal of Infectious Diseases, v. 16, n. 3, p. 219-225, 2012. | pt_BR |
| ISSN | 1413-8670 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/30343 | |
| Description | Artigo disponível para download no site do Editor. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Pseudomonas aeruginosa | pt_BR |
| Subject in Portuguese | Fatores de risco | pt_BR |
| Subject in Portuguese | Surto de doenças | pt_BR |
| Subject in Portuguese | Epidemiologia molecular | pt_BR |
| Subject in Portuguese | Imunodeficiência adquirida | pt_BR |
| Subject in Portuguese | Síndrome | pt_BR |
| Title | Factors associated with epidemic multiresistant Pseudomonas aeruginosa infections in a hospital with AIDS-predominant admissions | pt_BR |
| Type | Article | |
| DOI | 10.1590/S1413-86702012000300001 | pt_BR |
| Abstract | Introduction: Infections caused by multiresistant Pseudomonas aeruginosa (MR-PA) have been
associated with persistent infections and high mortality in acquired immunodeficiency
syndrome (AIDS) patients. Therefore, understanding the predisposing factors for infection/
colonization by this agent is critical for controlling outbreaks caused by MR-PA in settings
with AIDS patients.
Objective and methods: To analyze the presence of factors associated with the acquisition
of an epidemic MR-PA strain in a hospital with AIDS-predominant admission. A casecontrol
study was carried out in which cases and controls were gathered from a
prospective cohort of all hospitalized patients in an infectious disease hospital during
a five-year study period.
Results: Multivariate logistic regression analysis demonstrated that enteral nutrition
(OR = 14.9), parenteral nutrition (OR = 10.7), and use of ciprofloxacin (OR = 8.9) were
associated with a significant and independent risk for MR-PA acquisition.
Conclusions: Although cross-colonization was likely responsible for the outbreaks, the
use of ciprofloxacin was also an important factor associated with the acquisition of an
epidemic MR-PA strain. More studies are necessary to determine whether different types
of nutrition could lead to modification of gastrointestinal flora, thereby increasing the
risk for infection/colonization by MR-PA in this population. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ, Brasil / University of Texas. Department of Infectious Diseases, Infection Control and Employee Health. MD Anderson Cancer Center. Texas, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Comitê de Controle de Infecção. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Comitê de Controle de Infecção. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Comitê de Controle de Infecção. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Comitê de Controle de Infecção. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Comitê de Controle de Infecção. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Pseudomonas aeruginosa | pt_BR |
| Subject | Risk factors | pt_BR |
| Subject | Disease outbreaks | pt_BR |
| Subject | Molecular epidemiology | pt_BR |
| Subject | Acquired immunodeficiency | pt_BR |
| Subject | syndrome | pt_BR |
| e-ISSN | 1678-4391 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
