| Author | Van der Heijden, Yuri F. | |
| Author | Abdullah, Fareed | |
| Author | Andrade, Bruno de Bezerril | |
| Author | Andrews, Jason R | |
| Author | Christopher, Devasahayam J. | |
| Author | Croda, Julio | |
| Author | Ewing, Heather | |
| Author | Haas, David W. | |
| Author | Hatherill, Mark | |
| Author | Horsburgh, C. Robert | |
| Author | Mave, Vidya | |
| Author | Nakaya, Helder I. | |
| Author | Rolla, Valeria | |
| Author | Srinivasan, Sudha | |
| Author | Sugiyono, Retna Indah | |
| Author | Ugarte-Gil, Cesar | |
| Author | Hamilton, Carol | |
| Access date | 2018-12-07T16:31:14Z | |
| Available date | 2018-12-07T16:31:14Z | |
| Document date | 2018 | |
| Citation | VAN DER HEIJDEN, Yuri F. et al. Building capacity for advances in tuberculosis research; proceedings of the third RePORT international meeting. Tuberculosis, v. 113, p. 153-162, 2018. | pt_BR |
| ISSN | 1472-9792 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/30422 | |
| Sponsorship | National Institutes of Health (NIH) [K08 AI106420] and the U.S. Civilian Research and Development Foundation (CRDF) [OISE-16-62061-1]. Dr. Andrade was supported by the NIH [U01AI14018, R01AI20790], CRDF Global [DAA3-17-63145-1], Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB), and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Brazil [028/2010]. Drs. Andrews and Croda were supported by the NIH [R01AI130058], and Dr. Croda was also supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Brazil [401824/2016-0 and 420672/2017-6]. Dr. Haas was supported by the NIH [R01AI077505, P30 AI110527]. Dr. Hatherill was supported by CRDF Global [OISE-16-62054-1] and the South African Medical Research Council (SAMRC Collaborating Centre for TB and HIV). Dr. Horsburgh was supported by the Providence/Boston Center for AIDS Research [P30AI042853], the Boston University/Rutgers Tuberculosis Research Unit [U19AI111276], and the U.S.-India Vaccine Action Program (VAP) Initiative on Tuberculosis (CRDF Global/NIAID). Dr. Mave was supported by the Indo (DBT)-US (NIH) [USB1-31147-XX-13 CRDF/NIH], and the Johns Hopkins Baltimore-Washington-India Clinical Trials Unit for NIAID Networks [U01AI069497]. Dr. Sugiyono was supported by the NIAID at NIH [contract numbers HHSN261200800001E and HHSN261201500003I]. Dr. Ugarte-Gil was supported by the TANDEM project, which is funded by the European Union's Seventh Framework Programme (FP7/2007–2013) [305279]. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | restricted access | pt_BR |
| Subject in Portuguese | Transmissão | pt_BR |
| Subject in Portuguese | Farmacogenómica | pt_BR |
| Subject in Portuguese | Tuberculose incipiente | pt_BR |
| Subject in Portuguese | HIV | pt_BR |
| Subject in Portuguese | Diabetes | pt_BR |
| Subject in Portuguese | Biomarcadores | pt_BR |
| Title | Building capacity for advances in tuberculosis research; proceedings of the third RePORT international meeting | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.tube.2018.09.009 | |
| Abstract | RePORT International is a global network of research sites in India, Brazil, Indonesia, South Africa, China, and the Philippines dedicated to collaborative tuberculosis research in the context of HIV. A standardized research protocol (the Common Protocol) guides the enrollment of participants with active pulmonary tuberculosis and contacts into observational cohorts. The establishment of harmonized clinical data and bio-repositories will allow cutting-edge, large-scale advances in the understanding of tuberculosis, including identification of novel biomarkers for progression to active tuberculosis and relapse after treatment. The RePORT International infrastructure aims to support research capacity development through enabling globally-diverse collaborations. To that end, representatives from the RePORT International network sites, funding agencies, and other stakeholders gathered together in Brazil in September 2017 to present updates on relevant research findings and discuss ideas for collaboration. Presenters emphasized research involving biomarker identification for incipient tuberculosis, host immunity and pharmacogenomics, co-morbidities such as HIV and type 2 diabetes mellitus, and tuberculosis transmission in vulnerable and high-risk populations. Currently, 962 active TB participants and 670 household contacts have contributed blood, sputum, urine and microbes to in-country biorepositories. Cross-consortium collaborations have begun sharing data and specimens to analyze molecular and cytokine predictive patterns. | pt_BR |
| Affilliation | Vanderbilt University School of Medicine. Vanderbilt Tuberculosis Center. Nashville, TN, USA / Vanderbilt University School of Medicine. Department of Medicine. Division of Infectious Diseases. Nashville, TN, USA. | pt_BR |
| Affilliation | South African Medical Research Council. Office of AIDS and TB Research. Pretoria, South Africa. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / José Silveira Foundation. Multinational Organization Network Sponsoring Translational and Epidemiological Research Initiative. Salvador, BA, Brazil / University of Cape Town. Institute of Infectious Disease and Molecular Medicine. Wellcome Centre for Infectious Disease Research in Africa. Cape Town, South Africa / Vanderbilt University School of Medicine. Division of Infectious Diseases. Department of Medicine. Nashville, TN, USA / Universidade Salvador Laureate University. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil. | pt_BR |
| Affilliation | Stanford University School of Medicine. Department of Medicine. Division of Infectious Diseases and Geographic Medicine. Stanford, CA, USA. | pt_BR |
| Affilliation | Christian Medical College. Department of Pulmonary Medicine. Vellore, Tamilnadu, India. | pt_BR |
| Affilliation | Federal University of Mato Grosso do Sul. School of Medicine. Campo Grande, MS, Brazil / Oswaldo Cruz Foundation. Fiocruz Mato Grosso do Sul. Campo Grande, MS, Brazil. | pt_BR |
| Affilliation | Vanderbilt University. School of Medicine. Nashville, TN, USA. | pt_BR |
| Affilliation | Vanderbilt University School of Medicine. Departments of Medicine, Pharmacology, Pathology, Microbiology & Immunology. Nashville, TN, USA / Meharry Medical College. Department of Internal Medicine. Nashville, TN, USA. | pt_BR |
| Affilliation | University of Cape Town. Institute of Infectious Disease & Molecular Medicine and Division of Immunology. South African Tuberculosis Vaccine Initiative. Department of Pathology. Cape Town, South Africa. | pt_BR |
| Affilliation | Boston University School of Public Health. Department of Epidemiology. Boston, MA, USA / Boston University School of Medicine. Department of Medicine. Section of Infectious Diseases. Boston, MA, USA. | pt_BR |
| Affilliation | Hopkins University Clinical Research Site. Byramjee-Jeejeebhoy Government Medical College-Johns. Pune, India / Johns Hopkins University School of Medicine. Baltimore, MD, USA. | pt_BR |
| Affilliation | University of São Paulo. School of Pharmaceutical Sciences. Department of Clinical and Toxicological Analyses. São Paulo, SP, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica sobre Micobactérias. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | National Institutes of Health. National Institute of Allergy and Infectious Diseases. Division of AIDS. Bethesda, MD, USA. | pt_BR |
| Affilliation | Ministry of Health. National Institute of Health Research and Development. Indonesia. | pt_BR |
| Affilliation | Universidad Peruana Cayetano Heredia. Instituto de Medicina Tropical Alexander von Humboldt. Lima, Peru / Universidad Peruana Cayetano Heredia. School of Medicine. Lima, Peru / London School of Hygiene and Tropical Medicina. TB Centre. London, UK / Bloomberg School of Public Health. Department of International Health. Johns Hopkins Maryland, USA. | pt_BR |
| Affilliation | Duke University. Durham, NC, USA. | pt_BR |
| Subject | Transmission | pt_BR |
| Subject | Pharmacogenomics | pt_BR |
| Subject | Incipient tuberculosis | pt_BR |
| Subject | HIV | pt_BR |
| Subject | Diabetes | pt_BR |
| Subject | Biomarkers | pt_BR |
