| Author | Molina, Jean-Michel | |
| Author | Andrade-Villanueva, Jaime | |
| Author | Echevarria, Juan | |
| Author | Chetchotisakd, Ploenchan | |
| Author | Corral, Jorge | |
| Author | David, Neal | |
| Author | Moyle, Graeme | |
| Author | Mancini, Marco | |
| Author | Percival, Lisa | |
| Author | Yang, Rong | |
| Author | Thiry, Alexandra | |
| Author | McGrath, Donnie | |
| Author | CASTLE Study Team | |
| Access date | 2018-12-10T14:44:54Z | |
| Available date | 2018-12-10T14:44:54Z | |
| Document date | 2008 | |
| Citation | MOLINA, J. M. et al. Once-daily atazanavir/ritonavir versus twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 48 week efficacy and safety results of the CASTLE study. Lancet, v. 372, n. 9639, p. 646-655, 2008. | pt_BR |
| ISSN | 0140-6736 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/30481 | |
| Description | Presente no CASTLE Study Team: Beatriz Grinsztejn (Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil). | pt_BR |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Once-daily atazanavir/ritonavir versus twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 48 week efficacy and safety results of the CASTLE study | pt_BR |
| Type | Article | |
| DOI | 10.1016/S0140-6736(08)61081-8 | |
| Abstract | Atazanavir/ritonavir is as effective as lopinavir/ritonavir, with a more favourable lipid profile and less gastrointestinal toxicity, in treatment-experienced HIV-1-infected patients. We compared these two combinations directly in treatment-naive patients. | pt_BR |
| Affilliation | Saint-Louis Hospital. Department of Infectious Diseases. Paris./ University of Paris-Diderot, Paris, France. | pt_BR |
| Affilliation | Hospital Civil de Guadalajara. Guadalajara, Mexico. | pt_BR |
| Affilliation | Hospital Nacional Cayetano Heredia. Lima, Peru. | pt_BR |
| Affilliation | Khonkaen University. Department of Medicine. Khonkaen, Thailand. | pt_BR |
| Affilliation | Hospital Interzonal Gral De Agudos Oscar Alende. Buenos Aires, Argentina. | pt_BR |
| Affilliation | Brooklyn Medical Centre. Western Cape, South Africa. | pt_BR |
| Affilliation | Chelsea and Westminster Hospital. London, UK. | pt_BR |
| Affilliation | Bristol-Myers Squibb. Research and Development. Wallingford, CT, USA. | pt_BR |
| Affilliation | Bristol-Myers Squibb. Research and Development. Wallingford, CT, USA. | pt_BR |
| Affilliation | Bristol-Myers Squibb. Research and Development. Wallingford, CT, USA. | pt_BR |
| Affilliation | Bristol-Myers Squibb. Research and Development. Wallingford, CT, USA. | pt_BR |
| Affilliation | Bristol-Myers Squibb. Research and Development. Wallingford, CT, USA. | pt_BR |
| Subject | HIV | pt_BR |
| Subject | Atazanavir Sulfate | pt_BR |
| Subject | Lopinavir | pt_BR |
| Subject | Ritonavir | pt_BR |
| Subject | Drug Administration | pt_BR |
| Embargo date | 2028-08-30 | |
