| Author | Couto-Fernandez, José Carlos | |
| Author | Eyer-Silva, Walter A. | |
| Author | Guimarães, Monick L. | |
| Author | Chequer-Fernandez, Saada L. | |
| Author | Grinsztejn, Beatriz | |
| Author | Delaporte, Eric | |
| Author | Peeters, Martine | |
| Author | Morgado, Mariza G. | |
| Access date | 2019-01-28T12:13:03Z | |
| Available date | 2019-01-28T12:13:03Z | |
| Document date | 2006 | |
| Citation | COUTO-FERNANDEZ, José Carlos et al. Phylogenetic analysis of Brazilian HIV Type 1 subtype D strains: tracing the origin of this subtype in Brazil. AIDS Research and Human Retroviruses, v. 22, n. 2, p. 207-211, 2006. | pt_BR |
| ISSN | 0889-2229 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/31321 | |
| Language | eng | pt_BR |
| Publisher | Mary Ann Liebert | pt_BR |
| Rights | restricted access | |
| Title | Phylogenetic analysis of Brazilian HIV type 1 subtype D strains: tracing the origin of this subtype in Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1089/aid.2006.22.207 | |
| Abstract | HIV-1 Subtype D occurs mainly in East and Central African countries, especially Uganda, where the prevalence of HIV-1 infection is among the highest in the world. We present the phylogenetic analysis of one nonautochthonous and four autochthonous (including a near full-length genome) Brazilian HIV-1 subtype D strains identified in Rio de Janeiro State, where subtypes B, F1, and BF1 recombinants predominate. Phylogenetic inferences using maximum likelihood were applied on a near-full length genome and on concatenated gag, protease, reverse transcriptase, integrase, C2V3/env, gp41, and nef segments. Sequences from an Angolan immigrant showed close genetic similarity with a strain described in Finland, from an HIV patient of African origin, whereas all four autochthonous Brazilian sequences clustered with South African strains, where subtype D occurs only in isolated cases. Our results suggest the successful introduction and circulation in Brazil of closely related HIV-1 subtype D strains, possibly of South African origin. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil / Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisas Clínicas Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Institut de Recherche pour le Développement. Laboratoire Retrovírus. Montpellier, France. | pt_BR |
| Affilliation | Institut de Recherche pour le Développement. Laboratoire Retrovírus. Montpellier, France. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Phylogenetic analysis | pt_BR |
| Subject | HIV-1 | pt_BR |
| Subject | Brazilian HIV type 1 subtype D | pt_BR |
| e-ISSN | 1931-8405 | |
| Embargo date | 2028-01-01 | |
