| Author | Brewinski, Margaret | |
| Author | Megazzini, Karen | |
| Author | Hance, Laura Freimanis | |
| Author | Cruz, Miguel Cashat | |
| Author | Pavia-Ruz, Noris | |
| Author | Della Negra, Marinella | |
| Author | Ferreira, Flavia Gomes Faleiro | |
| Author | Marques, Heloisa | |
| Author | Hazra, Rohan | |
| Author | NISDI Pediatric Study Group 2010 | |
| Access date | 2019-02-28T18:23:00Z | |
| Available date | 2019-02-28T18:23:00Z | |
| Document date | 2011 | |
| Citation | BREWINSKI, Margaret et al. Dyslipidemia in a cohort of HIV-infected Latin American children receiving highly active antiretroviral therapy. Journal of Tropical Pediatrics, v. 57, n. 5, p. 324-32, 2010. | pt_BR |
| ISSN | 0142-6338 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/31948 | |
| Description | Presentes no NISDI Pediatric Study Group 2010: Beatriz Grinsztejn; Valdiléa Veloso (Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil). | pt_BR |
| Language | eng | pt_BR |
| Publisher | Oxford | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Dyslipidemia in a cohort of HIV-infected Latin American children receiving highly active antiretroviral therapy | pt_BR |
| Type | Article | |
| DOI | 10.1093/tropej/fmq089 | |
| Abstract | In order to describe the prevalence of hypercholesterolemia and hypertriglyceridemia in a cohort of HIV-infected children and adolescents in Latin America and to determine associations with highly active antiretroviral therapy (HAART), we performed this cross-sectional analysis within the NICHD International Site Development Initiative pediatric cohort study. Eligible children had to be at least 2 years of age and be on HAART. Among the 477 eligible HIV-infected youth, 98 (20.5%) had hypercholesterolemia and 140 (29.4%) had hypertriglyceridemia. In multivariable analyses, children receiving protease inhibitor (PI)-containing HAART were at increased risk for hypercholesterolemia [adjusted odds ratio (AOR) = 2.7, 95% confidence interval (CI) 1.3-5.6] and hypertriglyceridemia (AOR = 3.5, 95% CI 1.9-6.4) compared with children receiving non-nucleoside reverse transcriptase inhibitor (NNRTI)-containing HAART. In conclusion, HIV-infected youth receiving PI-containing HAART in this Latin American cohort were at increased risk for hypercholesterolemia and hypertriglyceridemia compared with those receiving NNRTI-containing HAART. | pt_BR |
| Affilliation | Pediatric, Adolescent and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD, USA./ Office of HIV/AIDS, The United States Agency for International Development, Washington, USA. | pt_BR |
| Affilliation | Westat. Rockville, MD, USA. | pt_BR |
| Affilliation | Westat. Rockville, MD, USA. | pt_BR |
| Affilliation | Clinica de Inmunodeficiencias/Depto. Infectología; Hospital Infantil de Mexico Federico Gomez, Mexico | pt_BR |
| Affilliation | Clinica de Inmunodeficiencias/Depto. Infectología; Hospital Infantil de Mexico Federico Gomez, Mexico | pt_BR |
| Affilliation | Instituto de Infectologia Emilio Ribas, Sao Paulo, Brazil. | pt_BR |
| Affilliation | School of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. | pt_BR |
| Affilliation | Instituto da Crianca – HCFM Universidade de Sao Paulo, Sao Paulo, Brazil. | pt_BR |
| Affilliation | Pediatric, Adolescent and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD, USA. | pt_BR |
| Subject | HIV | pt_BR |
| Subject | Cholesterol | pt_BR |
| Subject | Triglycerides | pt_BR |
| Subject | Pediatric | pt_BR |
| Embargo date | 2050-01-01 | |
