| Author | Lins, R. M. M. A. | |
| Author | Souza, N. A. | |
| Author | Peixoto, A. A. | |
| Access date | 2019-03-07T11:01:56Z | |
| Available date | 2019-03-07T11:01:56Z | |
| Document date | 2008 | |
| Citation | LINS, R. M. M. A.; SOUZA, N. A.; PEIXOTO, A. A. Genetic divergence between two sympatric species of the Lutzomyia longipalpis complex in the paralytic gene, a locus associated with insecticide resistance and lovesong production. Mem. Inst. Oswaldo Cruz, v.103, n.7, p.736-740, Nov. 2008. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/31957 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Lutzomyia longipalpis | pt_BR |
| Subject in Portuguese | Drosophila | pt_BR |
| Subject in Portuguese | Leishmaniose | pt_BR |
| Subject in Portuguese | Simpatria | pt_BR |
| Subject in Portuguese | Resistência a Inseticidas | pt_BR |
| Subject in Portuguese | Psychodidae | pt_BR |
| Title | Genetic divergence between two sympatric species of the Lutzomyia longipalpis complex in the paralytic gene, a locus associated with insecticide resistance and lovesong production | pt_BR |
| Type | Article | |
| Abstract | The sandfly Lutzomyia longipalpis s.l. is the main vector of American Visceral Leishmaniasis. L. longipalpis s.l.
is a species complex but until recently the existence of cryptic sibling species among Brazilian populations was a
controversial issue. A fragment of paralytic (para), a voltage dependent sodium channel gene associated with insecticide
resistance and courtship song production in Drosophila, was isolated and used as a molecular marker to
study the divergence between two sympatric siblings of the L. longipalpis complex from Sobral, Brazil. The results
revealed para as the first single locus DNA marker presenting fixed differences between the two species in this locality.
In addition, two low frequency amino-acid changes in an otherwise very conserved region of the channel were
observed, raising the possibility that it might be associated with incipient resistance in this vector. To the best of our
knowledge, the present study represents the first population genetics analysis of insecticide resistance genes in this
important leishmaniasis vector. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Leishmanioses. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | Lutzomyia longipalpis | pt_BR |
| Subject | Drosophila | pt_BR |
| Subject | para | pt_BR |
| Subject | Insecticide resistance | pt_BR |
| Subject | Leishmaniasis | pt_BR |
| Subject | Sandflies | pt_BR |
| Subject | Sympatric species | pt_BR |
| DeCS | Simpatria | pt_BR |
| e-ISSN | 1678-8060 | |
