Author | Henss, Lisa | |
Author | Yue, Constanze | |
Author | Kandler, Joshua | |
Author | Faddy, Helen M. | |
Author | Simmons, Graham | |
Author | Panning, Marcus | |
Author | Lewis-Ximenez, Lia Laura | |
Author | Baylis, Sally A. | |
Author | Schnierle, Barbara S. | |
Access date | 2019-03-07T12:49:09Z | |
Available date | 2019-03-07T12:49:09Z | |
Document date | 2019 | |
Citation | HENSS, Lisa et al. Establishment of an Alphavirus-Specific Neutralization Assay to Distinguish Infections with Different Members of the Semliki Forest Complex. Viruses, v. 11, n. 82, p. 1-13, 2019. | pt_BR |
ISSN | 1999-4915 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/31963 | |
Language | eng | pt_BR |
Publisher | MDPI | pt_BR |
Rights | open access | |
Subject in Portuguese | Pseudotipagem | pt_BR |
Subject in Portuguese | Vetor de lentivirus | pt_BR |
Subject in Portuguese | Ensaio de neutralização | pt_BR |
Subject in Portuguese | Alphavirus | pt_BR |
Title | Establishment of an Alphavirus-Specific Neutralization Assay to Distinguish Infections with Different Members of the Semliki Forest complex | pt_BR |
Type | Article | |
DOI | 10.3390/v11010082 | |
Abstract | Alphaviruses are transmitted by arthropod vectors and can be found worldwide. Alphaviruses of the Semliki Forest complex such as chikungunya virus (CHIKV), Mayaro virus (MAYV) or Ross River virus (RRV) cause acute febrile illness and long-lasting arthralgia in humans, which cannot be clinically discriminated from a dengue virus or Zika virus infection. Alphaviruses utilize a diverse array of mosquito vectors for transmission and spread. For instance, adaptation of CHIKV to transmission by Aedes albopictus has increased its spread and resulted in large outbreaks in the Indian Ocean islands. For many alphaviruses commercial diagnostic tests are not available or show cross-reactivity among alphaviruses. Climate change and globalization will increase the spread of alphaviruses and monitoring of infections is necessary and requires virus-specific methods. | pt_BR |
Affilliation | Paul-Ehrlich-Institut. Department of Virology. 63225 Langen, Germany. | pt_BR |
Affilliation | Paul-Ehrlich-Institut. Department of Virology. 63225 Langen, Germany. | pt_BR |
Affilliation | Paul-Ehrlich-Institut. Department of Virology. 63225 Langen, Germany. | pt_BR |
Affilliation | Australian Red Cross Blood Service. Brisbane, Australia. | pt_BR |
Affilliation | Vitalant Research Institute. San Francisco, CA, USA. | pt_BR |
Affilliation | University of Freiburg. Medical Center. Institute of Virology. Freiburg, Germany / University of Freiburg. Faculty of Medicine. Freiburg, Germany. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Paul-Ehrlich-Institut. Department of Virology. 63225 Langen, Germany. | pt_BR |
Affilliation | Paul-Ehrlich-Institut. Department of Virology. 63225 Langen, Germany. | pt_BR |
Subject | Alphavirus | pt_BR |
Subject | Neutralization assay | pt_BR |
Subject | Lentiviral vector | pt_BR |
Subject | Pseudotyping | pt_BR |
e-ISSN | 1999-4915 | |