| Author | Gremião, I. D. | |
| Author | Schubach, T. M. P. | |
| Author | Pereira, S. A. | |
| Author | Rodrigues, A. | |
| Author | Honse, C. | |
| Author | Barros, M. B. L. | |
| Access date | 2019-05-24T12:29:33Z | |
| Available date | 2019-05-24T12:29:33Z | |
| Document date | 2011 | |
| Citation | GREMIÃO, I. D. et al. Treatment of refractory feline sporotrichosis with a combination of intralesional amphotericin B and oral itraconazole. Australian Veterinary Journal, v. 89, n. 9, p. 346-351, 2011. | pt_BR |
| ISSN | 0005-0423 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/33203 | |
| Language | eng | pt_BR |
| Publisher | Wiley | pt_BR |
| Rights | open access | pt_BR |
| Title | Treatment of refractory feline sporotrichosis with a combination of intralesional amphotericin B and oral itraconazole | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1111/j.1751-0813.2011.00804.x | |
| Abstract | Objective: To describe the use of intralesional amphotericin B inlocalised lesions for the treatment of 26 cats from Rio de Janeiro, Brazil, with sporotrichosis refractory to oral itraconazole. Design: Uncontrolled intervention study. Method: The 26 cats in this study were diagnosed with sporotri-chosis, confirmed by isolation of Sporothrix schenckii, and presented residual localised skin lesions refractory to treatment with oral itraconazole for a minimum period of 8 weeks. The animals received weekly applications of intralesional amphotericin B in conjunction with oral itraconazole. In cases of owner unavailability, a maximumof 2 weeks between the infiltrations was accepted. Results: Twenty-two (84.6%) of the 26 treated cats achieved clini-cal remission, 16 (72.7%) of which were cured, and in the remainingsix (27.3%) the lesions recurred at the same site. Lack of clinical response was observed in one animal and three owners abandonedtreatment. Conclusion: The proposed therapeutic regimen is an adjunctive treatment option for cats with sporotrichosis presenting as residualskin lesions refractory to itraconazole. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Amphotericin B | pt_BR |
| Subject | Cats | pt_BR |
| Subject | Intralesional therapy | pt_BR |
| Subject | Itraconazole | pt_BR |
| Subject | Sporotrichosis | pt_BR |
| e-ISSN | 1751-0813 | |
| Embargo date | 2020-05-24 | |
