| Author | Rodrigues, Luana L. S. | |
| Author | Hardick, Justin | |
| Author | Nicol, Alcina F. | |
| Author | Morgado, Mariza G. | |
| Author | Martinelli, Katrini G. | |
| Author | Paula, Vanessa S. de | |
| Author | Pilotto, José H. | |
| Author | Gaydos, Charlotte A. | |
| Access date | 2019-06-04T12:56:03Z | |
| Available date | 2019-06-04T12:56:03Z | |
| Document date | 2019 | |
| Citation | RODRIGUES, Luana L. S. et al. Sexually transmitted infections among HIVinfected and HIV-uninfected women in the Tapajós region, Amazon, Brazil: self-collected vs. clinician-collected samples. Plos One, v. 14, n. 4, p. 1-21, Apr. 23, 2019. | pt_BR |
| ISSN | 1932-6203 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/33354 | |
| Language | eng | pt_BR |
| Publisher | Public Library of Science | pt_BR |
| Rights | open access | |
| Title | Sexually transmitted infections among HIV-infected and HIV-uninfected women in the Tapajós region, Amazon, Brazil: Self-collected vs. clinician-collected samples | pt_BR |
| Type | Article | |
| DOI | 10.1371/journal.pone.0215001 | |
| Abstract | The anogenital prevalence of sexually transmitted infections (STIs) and the use of cervico-vaginal self-collected vs. clinician-collected samples were evaluated for the diagnosis of human immunodeficiency virus (HIV)-infected and HIV-uninfected women in the Tapajós region, Amazon, Brazil. We recruited 153 women for a cross-sectional study (112 HIV-uninfected and 41 HIV-infected) who sought health services. Anal and cervical scrapings and cervico-vaginal self-collection samples were collected. Real-time polymerase chain reaction methods were used for Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis and Mycoplasma genitalium. A syphilis test was also performed. Risk factors for STIs were identified by multivariate analysis. The overall prevalence of STIs was 30.4% (34/112) in HIV-uninfected women and 24.4% (10/41) in HIV-infected women. Anogenital Chlamydia trachomatis infection was the most prevalent in both groups of women (20.5% vs 19.5%). There was significant agreement for each STI between self-collected and clinician-collected samples: 91.7%, kappa 0.67, 95% confidence interval (CI) 0.49-0.85 for Chlamydia trachomatis; 99.2%, kappa 0.85, 95% CI 0.57-1.00 for Neisseria gonorrhoeae; 97.7%, kappa 0.39, 95% CI -0.16-0.94 for Trichomonas vaginalis; and 94.7%, kappa 0.51, 95% CI 0.20-0.82 for Mycoplasma genitalium. Women with human papillomavirus had coinfection or multiple infections with other STIs. Risk factors for STIs were being ≤ 25 years old, being employed or a student, reporting a history of STI and having a positive HPV test. A high prevalence of STIs in women in the Tapajós region was found. Cervico-vaginal self-collection is a useful tool for STI screening and can be used in prevention control programs in low-resource settings, such as in northern Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil / Universidade Federal do Oeste do Pará. Instituto de Saúde Coletiva. Santarém, PA, Brasil. | pt_BR |
| Affilliation | Johns Hopkins University School of Medicine. Division of Infectious Diseases. Baltimore, MD, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Espírito Santo. Departamento de Medicina Social. Vitória, ES, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de e Virologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Johns Hopkins University School of Medicine. Division of Infectious Diseases. Baltimore, MD, USA. | pt_BR |
| Subject | HIV | pt_BR |
| Subject | Women | pt_BR |
| Subject | Tapajós region | pt_BR |
| Subject | Amazon | pt_BR |
| Subject | Brazil | pt_BR |
| e-ISSN | 1932-6203 | |
| xmlui.metadata.dc.subject.ods | 05 Igualdade de gênero | |
