| Author | Erber, Astrid Christine | |
| Author | Arana, Byron | |
| Author | Bennis, Issam | |
| Author | Salah, Afif Ben | |
| Author | Boukthir, Aicha | |
| Author | Noriega, Maria del Mar Castro | |
| Author | Cissé, Mamoudou | |
| Author | Cota, Gláucia Fernandes | |
| Author | Handjani, Farhad | |
| Author | Kebede, Mairie Guizaw | |
| Author | Lang, Trudie | |
| Author | Carvajal, Liliana López | |
| Author | Marsh, Kevin | |
| Author | Medina, Dalila Martinez | |
| Author | Plugge, Emma | |
| Author | Olliaro, Piero | |
| Access date | 2019-06-25T19:24:44Z | |
| Available date | 2019-06-25T19:24:44Z | |
| Document date | 2018 | |
| Citation | ERBER, Astrid Christine et al. An international qualitative study exploring patients' experiences of cutaneous leishmaniasis: study set-up and protocol. BMJ Open, v. 8, n. 6, p. 1-7, 2018. | pt_BR |
| ISSN | 2044-6055 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/33669 | |
| Language | eng | pt_BR |
| Publisher | BMJ Publishing Group Ltd | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Epidemiologia | pt_BR |
| Subject in Portuguese | Saúde pública | pt_BR |
| Subject in Portuguese | Medicina tropical | pt_BR |
| Title | An international qualitative study exploring patients' experiences of cutaneous leishmaniasis: study set-up and protocol | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1136/bmjopen-2017-021372 | |
| Abstract | INTRODUCTION: Lack of investments in drug development, lack of standardisation of clinical trials and the complexity of disease presentations contribute to the current lack of effective, safe and adapted treatments for cutaneous leishmaniasis (CL). One aspect concerns outcomes affecting patients' quality of life (QoL): these are hardly assessed in trials, despite potential functional and/or aesthetic impairment caused by CL, which typically affects disadvantaged and vulnerable people living in rural areas. Here, we describe the approach used to bring perspectives of patients with CL into designing and assessing treatments.
METHODS AND ANALYSIS: This international qualitative study uses interviews with patients to explore their experiences with CL to (1) elicit outcomes and eligibility criteria for clinical trials important to them and (2) to better understand their needs and views about the disease and their requirements and expectations from treatment. Here, we describe the set-up of this collaborative study and the protocol. Data collection is ongoing.The protocol includes study design, preparation, conduct and analysis of individual interviews with approximately 80 patients in seven countries (Burkina Faso, Brazil, two sites in Colombia, Iran, Morocco, Peru and Tunisia) where CL is prevalent. Principal investigators and sites were selected through an open call, and two workshops were organised for protocol development and training in conduct and analysis of qualitative health research. Patient recruitment aims at covering a maximum variation of experiences. Transcripts will be analysed to identify outcomes and eligibility criteria as well as further topics that are expected to emerge from the interviews, such as direct and indirect costs related to CL, its psychological impact, preferred modes of drug administration and traditional treatments.
ETHICS AND DISSEMINATION: The study received ethical approval by the responsible committees of each of the participating institutions. Findings will be disseminated through publication in peer-reviewed journals, scientific meetings and to participants and their communities. | pt_BR |
| Affilliation | Centre for Tropical Medicine and Global Health. Nuffield Department of Medicine. University of Oxford. Oxford, UK / Department of Epidemiology. Center for Public Health. Medical University of Vienna. Vienna, Austria. | pt_BR |
| Affilliation | Drugs for Neglected Diseases Initiative. Geneva, Switzerland. | pt_BR |
| Affilliation | National School of Public Health. Rabat, Morocco / Department of Public Health. Institute of Tropical Medicine. Antwerp, Belgium. | pt_BR |
| Affilliation | Institut Pasteur de Tunis.Tunis, Tunisia / Department of Family and Community Medicine. College of Medicine and Medical Sciences. Arabian Gulf University. Manama, Bahrain. | pt_BR |
| Affilliation | Institut Pasteur de Tunis.Tunis, Tunisia. | pt_BR |
| Affilliation | Centro Internacional de Entrenamiento de Investigaciones Médicas.Cali, Colombia/EDCTP/TDR Fellow. European Vaccine Initiative. Heidelberg, Germany. | pt_BR |
| Affilliation | Centre MURAZ. Bobo-Dioulasso, Burkina Faso. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Molecular Dermatology Research Center. Shiraz University of Medical Sciences. Shiraz, Iran. | pt_BR |
| Affilliation | Ayder Referral Hospital. College of Health Sciences. Mekelle University. Mekelle, Ethiopia. | pt_BR |
| Affilliation | Centre for Tropical Medicine and Global Health. Nuffield Department of Medicine. University of Oxford. Oxford, UK. | pt_BR |
| Affilliation | Programa de Estudio y Control de Enfermedades Tropicales. Universidad de Antioquia. Medellín, Colombia. | pt_BR |
| Affilliation | Centre for Tropical Medicine and Global Health. Nuffield Department of Medicine. University of Oxford. Oxford, UK. | pt_BR |
| Affilliation | Instituto de Medicina Tropical Alexander von Humboldt. Universidad Peruana Cayetano Heredia, Lima, Peru / Departamento de Enfermedades Infecciosas, Dermatológicas y Tropicales, Hospital Cayetano Heredia. Lima, Peru. | pt_BR |
| Affilliation | Centre for Tropical Medicine and Global Health. Nuffield Department of Medicine. University of Oxford. Oxford, UK. | pt_BR |
| Affilliation | Centre for Tropical Medicine and Global Health. Nuffield Department of Medicine. University of Oxford. Oxford, UK / Special Programme for Research & Training in Tropical Diseases. Geneva, Switzerland. | pt_BR |
| Subject | Epidemiology | pt_BR |
| Subject | Public health | pt_BR |
| Subject | Tropical medicine | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
