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AutorFonseca, Vagner
AutorLibin, Pieter J. K.
AutorTheys, Kristof
AutorFaria, Nuno Rodrigues
AutorNunes, Marcio Roberto Teixeira
AutorRestovic, Maria I.
AutorFreire, Murilo
AutorGiovanetti, Marta
AutorCuypers, Lize
AutorNowé, Ann
AutorAbecasis, Ana
AutorDeforche, Koen
AutorSantiago, Gilberto A.
AutorSiqueira, Isadora C. de
AutorSan, Emmanuel J.
AutorMachado, Kaliane Caldas de Brito
AutorAzevedo, Vasco
AutorFilippis, Ana Maria Bispo de
AutorCunha, Rivaldo Venâncio da
AutorPybus, Oliver G.
AutorVandamme, Anne-Mieke
AutorAlcantara, Luiz Carlos Junior
AutorOliveira, Tulio de
Fecha de acceso2019-07-08T14:05:44Z
Fecha de disponibilización2019-07-08T14:05:44Z
Fecha de publicación2019
ReferenciaFONSECA, Vagner et al. A computational method for the identification of Dengue, Zika and Chikungunya virus species and genotypes. PLoS Neglected Tropical Diseases, v. 13, n. 5, p. 1-15, 2019.pt_BR
ISSN1935-2727pt_BR
URIhttps://www.arca.fiocruz.br/handle/icict/33877
PromociónFunding: Supported by a research Flagship grant from the South African Medical Re-search Council (MRC-RFA-UFSP-01-2013/UKZN HIVEPI), a Royal Society Newton Advanced Fellowship (TdO), the VIROGENESIS project receives funding from the European Union’s Horizon 2020 Research and Innovation Programme (under Grant Agreement no. 634650) and the National Institutes of Health Common Fund, grant number U24HG006941. Pieter Libin was supported by a PhD grant of the FWO (Fonds Wetenschappelijk Onderzoek -Vlaanderen). This work was supported by Decit/SCTIE/MoH and CNPq (440685/2016-8 and 440856/2016-7); by CAPES (88887.130716/2016-00, 88881.130825/2016-00 and 88887.130823/2016-00); and by EU’s Horizon 2020 Programme through ZIKAlliance (PRES-005-FEX-17-4-2-33). Ana Abecasis was supported by Fundação para a Ciência e Tecnologia (FCT) through funds to GHTM-UID/Multi/04413/2013. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing interests: Dr. Koen Deforche is one of the owners of the commercial company, EMWEB.pt_BR
Idiomaengpt_BR
EditorPublic Library of Sciencept_BR
Derechos de autoropen access
Palabras clave en PortuguésVírus da denguept_BR
Palabras clave en PortuguésZika viruspt_BR
Palabras clave en PortuguésChikungunyapt_BR
Palabras clave en PortuguésGenótipospt_BR
Palabras clave en PortuguésSoftwarept_BR
Palabras clave en PortuguésPrevençãopt_BR
Palabras clave en PortuguésTratamentopt_BR
TítuloA computational method for the identification of Dengue, Zika and Chikungunya virus species and genotypespt_BR
Tipo del documentoArticle
DOI10.1371/journal.pntd.0007231
Resumen en InglésIn recent years, an increasing number of outbreaks of Dengue, Chikungunya and Zika viruses have been reported in Asia and the Americas. Monitoring virus genotype diversity is crucial to understand the emergence and spread of outbreaks, both aspects that are vital to develop effective prevention and treatment strategies. Hence, we developed an efficient method to classify virus sequences with respect to their species and sub-species (i.e. serotype and/or genotype). This tool provides an easy-to-use software implementation of this new method and was validated on a large dataset assessing the classification performance with respect to whole-genome sequences and partial-genome sequences. Available online: http://krisp.org.za/tools.php.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil / University of KwaZuluNatal. College of Health Sciences. KwaZulu-Natal Research Innovation and Sequencing Platform. Durban, South Africa / Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil.pt_BR
AfiliaciónVrije Universiteit Brussel. Artificial Intelligence Lab. Department of Computer Science. Brussels, Belgium / KU Leuven-University of Leuven. Rega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium.pt_BR
AfiliaciónKU Leuven-University of Leuven. Rega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium.pt_BR
AfiliaciónUniversity of Oxford. Department of Zoology. Oxford, United Kingdom.pt_BR
AfiliaciónMinistry of Health. Evandro Chagas Institute. Ananindeua, Brazil.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil.pt_BR
AfiliaciónKU Leuven-University of Leuven. Rega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium.pt_BR
AfiliaciónVrije Universiteit Brussel. Artificial Intelligence Lab. Department of Computer Science. Brussels, Belgium.pt_BR
AfiliaciónUniversidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Center for Global Health and Tropical Medicine. Unidade de Microbiologia. Lisbon, Portugal.pt_BR
AfiliaciónEMWEB. Private Company. Herent, Belgium.pt_BR
AfiliaciónCenters for Disease Control and Prevention. Division of Vector-Borne Diseases. San Juan, Puerto Rico, United states of America.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil.pt_BR
AfiliaciónUniversity of KwaZuluNatal. College of Health Sciences. KwaZulu-Natal Research Innovation and Sequencing Platform. Durban, South Africa.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil.pt_BR
AfiliaciónUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil / University of KwaZuluNatal. College of Health Sciences. KwaZulu-Natal Research Innovation and Sequencing Platform. Durban, South Africa / Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil.pt_BR
AfiliaciónFundação Oswaldo Cruz. Coordenação de Vigilância em Saúde e Laboratórios de Referências. Rio de Janeiro, RJ, Brasil.pt_BR
AfiliaciónUniversity of Oxford. Department of Zoology. Oxford, United Kingdom.pt_BR
AfiliaciónKU Leuven-University of Leuven. Rega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium / Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Center for Global Health and Tropical Medicine. Unidade de Microbiologia. Lisbon, Portugal.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil / Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil.pt_BR
AfiliaciónUniversity of KwaZuluNatal. College of Health Sciences. KwaZulu-Natal Research Innovation and Sequencing Platform. Durban, South Africa.pt_BR
Palavras clave en InglêsDengue viruspt_BR
Palavras clave en InglêsZika viruspt_BR
Palavras clave en InglêsChikungunyapt_BR
Palavras clave en InglêsGenotypept_BR
Palavras clave en InglêsSoftwarept_BR
Palavras clave en InglêsPreventionpt_BR
Palavras clave en InglêsTreatmentpt_BR


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