| Author | Vitral, Claudia L. | |
| Author | Yoshida, Clara F. T. | |
| Author | Lemos, Elba Regina S. | |
| Author | Teixeira, Christiane S. | |
| Author | Gaspar, Ana M. C. | |
| Access date | 2019-07-09T16:30:42Z | |
| Available date | 2019-07-09T16:30:42Z | |
| Document date | 1998 | |
| Citation | VITRAL, Claudia L. et al. Age-specific Prevalence of Antibodies to Hepatitis A in Children and Adolescents from Rio de Janeiro, Brazil, 1978 and 1995. Relationship of Prevalence to Environmental Factors. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 93, n. 1, p.1-5, Jan./Feb. 1998. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/33923 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Vírus da Hepatite A | pt_BR |
| Subject in Portuguese | Soroepidemiologia | pt_BR |
| Subject in Portuguese | Anticorpos | pt_BR |
| Subject in Portuguese | Crianças | pt_BR |
| Subject in Portuguese | Adolescentes | pt_BR |
| Subject in Portuguese | Rio de Janeiro | pt_BR |
| Subject in Portuguese | Fatores ambientais | pt_BR |
| Title | Age-specific Prevalence of Antibodies to Hepatitis A in Children and Adolescents from Rio de Janeiro, Brazil, 1978 and 1995. Relationship of Prevalence to Environmental Factors | pt_BR |
| Type | Article | |
| DOI | 10.1590/S0074-02761998000100001 | pt_BR |
| Abstract | The age-specific prevalence of antibodies to hepatitis A virus (anti-HAV) was determined in two different population groups with low socio-economic status from Rio de Janeiro city, Brazil, whose serum samples were collected 17 years apart (Population 1, 1978; Population 2, 1995). In Population
2, analysis of the anti-HAV prevalence was also carried out with respect to environmental factors. Population 1 was composed of 520 stored sera collected from the umbilical cord of term neonates and children aged 1 month to 6 years. In population 2, 720 serum samples were collected from children and adolescents with ages ranging from 1 to 23 years. The overall prevalence rate of anti-HAV in Population 1 and Population 2 was 65.6% and 32.1%, respectively. In Population 1, the anti-HAV prevalence
reached 88% at the age of 3, while in Population 2, it increased from 4.5% in children under the age of 3 to 66% in the group of adolescents over the age of 14. The low exposure to HAV infection in younger children from Population 2 could be a result of improved environmental hygiene and sanitation, as demonstrated by the presence of piped water, waste and sewage disposal systems in most houses from this population group. These findings indicate a possible change in the prevalence of hepatitis A in Rio
de Janeiro. | pt_BR |
| Affilliation | Universidade Federal Fluminense. Centro de Ciências Médicas. Departamento de Microbiologia e Parasitologia. Niterói, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Universidade Federal Fluminense. Centro de Ciências Médicas. Departamento de Microbiologia e Parasitologia. Niterói, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | Hepatitis A | pt_BR |
| Subject | Seroepidemiology | pt_BR |
| Subject | Anti-HAV | pt_BR |
| Subject | Antibodies | pt_BR |
| Subject | Children | pt_BR |
| Subject | Adolescents | pt_BR |
| Subject | Environmental Factors | pt_BR |
| Subject | Rio de Janeiro | pt_BR |
| e-ISSN | 1678-8060 | |
