| Author | Devera, Rodolfo | |
| Author | Fernandes, Octavio | |
| Author | Coura, José Rodrigues | |
| Access date | 2019-07-11T12:02:35Z | |
| Available date | 2019-07-11T12:02:35Z | |
| Document date | 2003 | |
| Citation | DEVERA, Rodolfo; FERNANDES, Octavio; COURA, José Rodrigues. Should Trypanosoma cruzi be Called cruzi Complex? A Review of the Parasite Diversity and the Potential of Selecting Population after in Vitro Culturing and Mice Infection. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 1, p. 1-12, Jan. 2003. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/33970 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Diversidade genética | pt_BR |
| Title | Should Trypanosoma cruzi be Called cruzi Complex? A Review of the Parasite Diversity and the Potential of Selecting Population after in Vitro Culturing and Mice Infection | pt_BR |
| Type | Article | |
| DOI | 10.1590/S0074-02762003000100001 | pt_BR |
| Abstract | Morpho-biological diversity of Trypanosoma cruzi has been known since Chagas’ first works in 1909. Several further studies confirmed the morphological differences among the parasite strains, which were isolated from different reservoirs and vectors, as well as from human beings. In the early sixties, antigenic differences were found in the parasite strains from various sources. These differences, coupled to the observation of regional variations of the disease, led to the proposal of the term cruzi complex to designate the taxon T. cruzi. Since then this protozoan has been typed in distinct biodemes, zymodemes and lineages which were consensually grouped into T. cruzi I, T. cruzi II and into non-grouped strains. T. cruzi genotypic characterization, initially carried out by schizodeme analysis and
more recently by various other techniques, has shown a great diversity of the parasite strains. In fact, T. cruzi is formed by groups of heterogeneous sub-population, which present specific characteristics, including distinct histotropism. The interaction of the different infecting clones of the cruzi complex and the human host will determine the morbidity of the disease. | pt_BR |
| Affilliation | Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical Rio de Janeiro, RJ. Brasil / Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| Subject | “cruzi” complex | pt_BR |
| Subject | Genetic diversity | pt_BR |
| e-ISSN | 1678-8060 | |
| xmlui.metadata.dc.subject.ods | 10 Redução das desigualdades | |
