| Author | Ribeiro, Camilla R. de Almeida | |
| Author | Amado, Luciane A. | |
| Author | Tourinho, Renata S. | |
| Author | LIma, Lyana R. Pinto | |
| Author | Melgaço, Juliana G. | |
| Author | Almeida, Adilson J. de | |
| Author | Bastos, Leonardo S. | |
| Author | Lewis-Ximenez, Lia L. | |
| Author | Paula, Vanessa S. de | |
| Access date | 2019-07-16T13:55:25Z | |
| Available date | 2019-07-16T13:55:25Z | |
| Document date | 2019 | |
| Citation | RIBEIRO, Camilla R. de Almeida et al. Accuracy of rapid test for diagnosis of hepatitis a with different infection rate settings and with predictive modeling. Future Microbiology, v. 14, n. 3, p. 247-258, 2019. | pt_BR |
| ISSN | 1746-0913 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/34143 | |
| Language | eng | pt_BR |
| Publisher | Future Medicine | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Anticorpos contra a hepatite A | pt_BR |
| Subject in Portuguese | Estudos de soroepidemiologia | pt_BR |
| Subject in Portuguese | Surto | pt_BR |
| Subject in Portuguese | Teste imunocromatográfico rápido | pt_BR |
| Subject in Portuguese | Vacina | pt_BR |
| Title | Accuracy of rapid test for diagnosis of hepatitis A with different infection rate settings and with predictive modeling | pt_BR |
| Type | Article | |
| DOI | 10.2217/fmb-2018-0211 | pt_BR |
| Abstract | Background: Chikungunya virus (CHIKV) and Mayaro virus (MAYV) are closely related members of the Semliki Forest complex within the genus alphavirus and are transmitted by arthropods, causing acute febrile illness in humans. CHIKV has spread to almost all continents, whereas autochthonous MAYV infections have been reported in South America and in the Caribbean. Nevertheless, there was concern about potential spread of MAYV to other regions similar to CHIKV in the past. The risk for transmission of emerging viruses by blood transfusion and the safety of
plasma-derived medicinal products (PDMPs) are constant concerns. The manufacturing processes of PDMPs include procedures to inactivate/remove viruses. Methods: In this study, we investigated
the reduction of MAYV and CHIKV by heat inactivation in various matrices, solvent/detergent treatment and nanofiltration. Results: Unexpectedly, MAYV was significantly more resistant to heat and solvent/detergent treatment compared to CHIKV. However, being similar in size, both
MAYV and CHIKV were removed below the detection limit by 35 nm virus filters. Conclusions: The inactivation profiles of different alphavirus members vary considerably, even within the Semliki Forest Complex. However, robust dedicated viral inactivation/removal procedures commonly used in the
plasma product industry are effective in inactivating or removing MAYV and CHIKV. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffreé Guinle. Departamento de Medicina Geral. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Ambulatório Clínico de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | Hepatitis A antibodies | pt_BR |
| Subject | Outbreak | pt_BR |
| Subject | Rapid immunochromatographic test | pt_BR |
| Subject | Seroepidemiology studies | pt_BR |
| Subject | Vaccine | pt_BR |
| e-ISSN | 1746-0921 | |
| Embargo date | 2025-01-01 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
