| Author | Yue, Constanze | |
| Author | Teitz, Sebastian | |
| Author | Miyabashi, Tomoyuki | |
| Author | Boller, Klaus | |
| Author | Lewis-Ximenez, Lia Laura | |
| Author | Baylis, Sally A. | |
| Author | Blümel, Johannes | |
| Access date | 2019-07-16T14:15:35Z | |
| Available date | 2019-07-16T14:15:35Z | |
| Document date | 2019 | |
| Citation | YUE, Constanze et al. Inactivation and Removal of Chikungunya Virus and Mayaro Virus from Plasma-derived Medicinal Products. Viruses, v. 11, n. 234, p. 1-13, 2019. | pt_BR |
| ISSN | 1999-4915 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/34147 | |
| Language | eng | pt_BR |
| Publisher | MDPI | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Alphavirus | pt_BR |
| Subject in Portuguese | Nanofiltração | pt_BR |
| Subject in Portuguese | Inativação | pt_BR |
| Subject in Portuguese | Vírus Chikungunya | pt_BR |
| Subject in Portuguese | Tratamento S / D | pt_BR |
| Subject in Portuguese | Tratamento térmico | pt_BR |
| Subject in Portuguese | Filtragem retentiva de vírus | pt_BR |
| Subject in Portuguese | Mayaro vírus | pt_BR |
| Subject in Portuguese | Medicamentos derivados de plasma | pt_BR |
| Title | Inactivation and Removal of Chikungunya Virus and Mayaro Virus from Plasma-derived Medicinal Products | pt_BR |
| Type | Article | |
| DOI | 10.3390/v11030234 | |
| Abstract | Chikungunya virus (CHIKV) and Mayaro virus (MAYV) are closely related members of the Semliki Forest complex within the genus alphavirus and are transmitted by arthropods, causing acute febrile illness in humans. CHIKV has spread to almost all continents, whereas autochthonous MAYV infections have been reported in South America and in the Caribbean. Nevertheless, there was concern about potential spread of MAYV to other regions similar to CHIKV in the past. The risk for transmission of emerging viruses by blood transfusion and the safety of plasma-derived medicinal products (PDMPs) are constant concerns. The manufacturing processes of PDMPs include procedures to inactivate/remove viruses. | pt_BR |
| Affilliation | Paul-Ehrlich-Institut. Department of Virology. Langen, Germany. | pt_BR |
| Affilliation | Asahi Kasei. Cologne, Germany. | pt_BR |
| Affilliation | Asahi Kasei. Cologne, Germany. | pt_BR |
| Affilliation | Paul-Ehrlich-Institut. Department of Virology. Langen, Germany. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Paul-Ehrlich-Institut. Department of Virology. Langen, Germany. | pt_BR |
| Affilliation | Paul-Ehrlich-Institut. Department of Virology. Langen, Germany. | pt_BR |
| Subject | Alphaviruses | pt_BR |
| Subject | Inactivation | pt_BR |
| Subject | Heat treatment | pt_BR |
| Subject | S/D treatment | pt_BR |
| Subject | Chikungunya virus | pt_BR |
| Subject | Mayaro virus | pt_BR |
| Subject | Virus retentive filtration | pt_BR |
| Subject | Nanofiltration | pt_BR |
| Subject | Plasma-derived medicinal products | pt_BR |
| DeCS | Nanofiltração | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
