| Author | Amorim, G. Moreira | |
| Author | Sodré, C. | |
| Author | Falcão, E. Mastrangelo Marinho | |
| Author | Cuzzi, T. | |
| Author | Fernandes, R. Timbó | |
| Author | Ramos-e-Silva, M. | |
| Access date | 2019-07-18T13:30:48Z | |
| Available date | 2019-07-18T13:30:48Z | |
| Document date | 2018 | |
| Citation | AMORIM, Gustavo Moreira et al. Glomeruloid hemangioma as a late manifestation of POEMS syndrome. Acta Dermatovenerologica Croatica, v. 26, n. 4, p. 321-324, 2018. | pt_BR |
| ISSN | 1330-027X | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/34227 | |
| Description | Tullia Cuzzi. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Croatian Medical Association | pt_BR |
| Rights | open access | pt_BR |
| Title | Glomeruloid hemangioma as a late manifestation of POEMS syndrome | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1111/j.1365-2230.2008.02997.x | |
| Abstract | Glomeruloid hemangiomas were first described by Chan in 1990 as a cutaneous marker of POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal proteinemia, and Skin changes). POEMS syndrome is a multisystem disease with a significant cutaneous involvement. Among its manifestations, hemangiomas are common, observed in up to one third of the patients, and, although specific, the
glomeruloid subtype is very rare. The vascular endothelium growth factor (VEGF) is an angiogenic stimulation factor, which also induces increased systemic vascular permeability. Thus, a scenario of overexpression of VEGF can credibly lead to the assumption of an association between cutaneous hemangiomas and systemic manifestations, implying prognostic and therapeutic considerations and reinforcing the importance of dermatological periodical consultations for these patients. We report the case of a patient in whom glomeruloid hemangiomas marked the recurrence of POEMS syndrome, occurring before the systemic symptoms. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Subject | POEMS syndrome | pt_BR |
| Subject | Glomeruloid hemangioma | pt_BR |
| Subject | Vascular endothelium growth factor | pt_BR |
| Subject | VEGF | pt_BR |
| e-ISSN | 1847-6538 | |
