| Author | Marques, Ana Paula C. | |
| Author | Oliveira, Sandra Maria V. L. | |
| Author | Rezende, Grazielli R. | |
| Author | Melo, Dayane A. | |
| Author | Fernandes-Fitts, Sonia M. | |
| Author | Pontes, Elenir Rose J. C. | |
| Author | Bonecini-Almeida, Maria da Glória | |
| Author | Camargo, Zoilo P. | |
| Author | Mendes, Rinaldo P. | |
| Author | Paniago, Anamaria M. M. | |
| Access date | 2019-07-26T12:32:02Z | |
| Available date | 2019-07-26T12:32:02Z | |
| Document date | 2017 | |
| Citation | MARQUES, Ana Paula C. et al. Standardization and prevalence of the booster phenomenon: evaluation using a two-step skin test with 43 kDa glycoprotein in individuals from an endemic region of paracoccidioidomycosis. Mycopathologia, v. 182, p. 809-817, 2017. | pt_BR |
| ISSN | 0301-486X | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/34436 | |
| Language | eng | pt_BR |
| Publisher | Springer Verlag | pt_BR |
| Rights | open access | pt_BR |
| Title | Standardization and prevalence of the booster phenomenon: evaluation using a two-step skin test with 43 kDa glycoprotein in individuals from an endemic region of paracoccidioidomycosis | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1007/s11046-017-0159-z | |
| Abstract | Background: We estimated the occurrence rate of the booster phenomenon by using an intradermal test with
43 kDa glycoprotein in an endemic area of paracoccidioidomycosis in the central-west region of Brazil. Methods: Individuals who had a negative result on a survey performed by using an intradermal test with 43 kDa glycoprotein in an endemic area of paracoccidioidomycosis underwent a second intradermal test after 10–15 days to determine the presence or absence of the booster phenomenon. Statistical analyses were performed using the Chi-square test, Chi-square for linear trend test, Student’s t test, and binomial test; p\0.05 was considered significant. Results: For the first time, we reported the occurrence of the booster phenomenon to an intradermal reaction caused by 43 kDa glycoprotein at a rate of 5.8–8.4%, depending on the test’s cutoff point. This suggests that a cutoff point should be considered for the booster phenomenon in intradermal tests with 43 kDa glycoprotein: a difference of 6–7 mm between readings according to the first and second tests, depending on the purpose of the evaluation. Conclusion: The results indicate that the prevalence of paracoccidioidal infection in endemic areas is underestimated, as the booster phenomenon has not been considered in epidemiological surveys for this infection. | pt_BR |
| Affilliation | Federal University of Mato Grosso do Sul. Faculty of Medicine. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Federal University of Mato Grosso do Sul. Faculty of Medicine. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Federal University of Mato Grosso do Sul. Faculty of Medicine. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Federal University of Mato Grosso do Sul. Faculty of Medicine. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Federal University of Mato Grosso do Sul. Faculty of Medicine. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Federal University of Mato Grosso do Sul. Faculty of Medicine. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Nacional de Infectologia Evandro Chagas. Laboratório de Imunologia e Imunogenética em Doenças Infecciosas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Federal University of São Paulo. Faculty of Medicine. Clinical Hospital. São Paulo, SP, Brazil. | pt_BR |
| Affilliation | Paulista State University. Faculty of Medicine of Botucatu. Tropical Disease Department. Botucatu, SP, Brazil. | pt_BR |
| Affilliation | Federal University of Mato Grosso do Sul. Faculty of Medicine. Campo Grande, MS, Brasil. | pt_BR |
| Subject | Paracoccidioidic infection | pt_BR |
| Subject | Booster phenomenon | pt_BR |
| Subject | Intradermal tests | pt_BR |
| Subject | Paracoccidioides brasiliensis | pt_BR |
| Subject | Paracoccidioidomycosis | pt_BR |
| Subject | gp43 | pt_BR |
| e-ISSN | 1573-0832 | |
| Embargo date | 2020-07-26 | |
