| Author | Duarte, Fernanda Gross | |
| Author | Moreira, Sandra da Silva | |
| Author | Almeida, Maria da Conceição Chagas de | |
| Author | Teles, Carlos A de Souza | |
| Author | Andrade, Carine de Sousa | |
| Author | Reingold, Art L. | |
| Author | Moreira Junior, Edson Duarte | |
| Access date | 2019-08-06T16:36:12Z | |
| Available date | 2019-08-06T16:36:12Z | |
| Document date | 2019 | |
| Citation | DUARTE, Fernanda Gross et al. Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela. BMJ Open, v. 9, p. 1-8, 2019. | pt_BR |
| ISSN | 0959-8138 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/34626 | |
| Sponsorship | Pfizer Inc. The Brazilian Study of Diabetes Control was funded by Pfizer Inc., Brazil. Coordination for the Improvement of Higher Education
Personnel (CAPES), Brazilian Ministry of Education. EDMJ received support from the National Council for Scientific and Technological Development (CNPq). | pt_BR |
| Language | eng | pt_BR |
| Publisher | BMJ Publishing Group | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Diabetes tipo 2 | pt_BR |
| Subject in Portuguese | Diferenças sexuais | pt_BR |
| Subject in Portuguese | Indice glicêmico | pt_BR |
| Subject in Portuguese | Humanos | pt_BR |
| Title | Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1136/bmjopen-2018-023401 | |
| Abstract | Examine whether glycaemic control varies according to sex and whether the latter plays a role in modifying factors associated with inadequate glycaemic control in patients with type 2 diabetes (T2D) in Brazil and Venezuela. Design, setting and participants This was a crosssectional, nationwide survey conducted in Brazil and Venezuela from February 2006 to June 2007 to obtain information about glycaemic control and its determinants in patients with diabetes mellitus attending outpatient clinics. Main outcome measures Haemoglobin A1c (HbA1c) level was measured by liquid chromatography, and patients with HbA1c ≥7.0% (53 mmol/mol) were considered to have inadequate glycaemic control. The association of
selected variables with glycaemic control was analysed by multivariate linear regression, using HbA1c as the dependent variable. Results A total of 9418 patients with T2D were enrolled in Brazil (n=5692) and in Venezuela (n=3726). They included 6214 (66%) women and 3204 (34%) men. On average, HbA1c levels in women were 0.13 (95% CI 0.03 to 0.24;
p=0.015) higher than in men, after adjusting for age, marital status, education, race, country, body mass index, duration of disease, complications, type of healthcare, adherence to diet, adherence to treatment and previous measurement of HbA1c. Sex modified the effect of some
factors associated with glycaemic control in patients with T2D in our study, but had no noteworthy effect in others. Conclusions Women with T2D had worse glycaemic control than men. Possible causes for poorer glycaemic
control in women compared with men include differences in glucose homeostasis, treatment response and psychological factors. In addition, sex modified factors associated with glycaemic control, suggesting the need to
develop specific treatment guidelines for men and women. | pt_BR |
| Affilliation | University of California. School of Public Health. Department of Epidemiology. Berkeley, CA, USA. | pt_BR |
| Affilliation | Associação Obras Sociais Irmã Dulce. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil / Universidade Federal da Bahia. Escola de Nutrição. Departamento Ciências da Nutrição. Salvador, BA, Brasil. | pt_BR |
| Affilliation | University of California. School of Public Health. Department of Epidemiology. Berkeley, CA, USA. | pt_BR |
| Affilliation | Associação Obras Sociais Irmã Dulce. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil. | pt_BR |
| Subject | Diabetes Mellitus, Type 2 | pt_BR |
| Subject | Sex Characteristics | pt_BR |
| Subject | Glycemic Index | pt_BR |
| Subject | Humans | pt_BR |
| xmlui.metadata.dc.subject.ods | 05 Igualdade de gênero | |
