| Autor | Ferreira, Léa Maria dos Santos Lopes | |
| Autor | Vale, Ademir Evangelista do | |
| Autor | Souza, Amancio José de | |
| Autor | Leite, Kelly Batista | |
| Autor | Sacramento, Cássia | |
| Autor | Moreno, Maria Lucia Vieira | |
| Autor | Araújo, Thessika Hialla | |
| Autor | Soares, Milena Botelho Pereira | |
| Autor | Grassi, Maria Fernanda Rios | |
| Data de acesso | 2019-08-23T12:32:01Z | |
| Data de disponibilização | 2019-08-23T12:32:01Z | |
| Data do publicação | 2019 | |
| Citação | FERREIRA, Léa Maria dos Santos Lopes et al. Anatomical and phytochemical characterization of Physalis angulata L.: A plant with therapeutic potential. Pharmacognosy Research, v. 11, n. 2, p. 171-177, 2019. | |
| ISSN | 0976-4836 | |
| URI | https://www.arca.fiocruz.br/handle/icict/35009 | |
| Fomento | FAPESB | |
| Idioma | eng | en_US |
| Editor | Medknow Publications | |
| Direito Autoral | open access | |
| Palavras-chave | Anatomia | pt_BR |
| Palavras-chave | Botânica | pt_BR |
| Palavras-chave | Microscopia eletrônica | pt_BR |
| Palavras-chave | Fotoquímica | pt_BR |
| Palavras-chave | Physalis angulata | pt_BR |
| Título | Anatomical and phytochemical characterization of Physalis angulata L.: A plant with therapeutic potential | en_US |
| Tipo do documento | Preprint | |
| Resumo em Inglês | Physalis angulata L. is widely used in folk medicine. Secondary metabolites with pharmacological potential, including physalins that exhibit anti-inflammatory/immunomodulatory and antiparasitic activities, have been identified in this specie. To date, few studies have investigated storage sites for secondary metabolites in P. angulata. Objective: The objective of the study is to characterize the anatomical structures and determine the phytochemical composition of the vegetative organs of P. angulata. Materials and Methods: Electron and conventional optical microscopy was used for the anatomical characterization of P angulata organs (leaves, roots, stems, and fruits). Methanolic extracts from leaves, roots, stems, and fruits were chemically characterized for the presence of steroids, terpenoids, tannins, alkaloids, saponins, flavonoids, anthraquinones, coumarins, and phenolic compounds. Phenolic compounds, flavonoid contents, and antioxidant capacity of these extracts were determined by 2,2-diphenyl-1-picrylhydrazyl-free radical scavenging activity. Results: Abaxial leaf stomata were more abundant than the adaxial stomata. Trichomes were more abundant along veins in the petioles and stems, beyond the margin in the sepals and petals, and dispersed in the ovary. Steroids and terpenoids were present in leaves, stems, and fruits of P. angulata. Saponins were exclusive to fruits. Phytochemical screening did not detect flavonoids, anthraquinones, and alkaloids in all tested plant parts. The highest antioxidant capacities were identified in leaf and fruit extracts, possibly due to the presence of phenolic compounds in these organs. Conclusion: This study describes anatomical and biochemical features from P angulata that will assist in future phytochemistry and pharmacological studies, particularly pointing toward organs abundant in antioxidants (leaves and fruits) and steroids (possibly physalins; leaves). | en_US |
| Afiliação | Bahian School of Medicine and Public Health. Salvador, BA, Brazil. | |
| Afiliação | Federal University of Bahia. Faculty of Pharmacy. Salvador, BA, Brazil. | |
| Afiliação | Bahian School of Medicine and Public Health. Salvador, BA, Brazil. | |
| Afiliação | Federal University of Bahia. Biology Institute. Salvador, BA, Brazil. | |
| Afiliação | Federal University of Bahia. Biology Institute. Salvador, BA, Brazil. | |
| Afiliação | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | |
| Afiliação | Bahian School of Medicine and Public Health. Salvador, BA, Brazil. | |
| Afiliação | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | |
| Afiliação | Bahian School of Medicine and Public Health. Salvador, BA, Brazil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | |
| Palavras-chave em inglês | Anatomy | en_US |
| Palavras-chave em inglês | Botany | en_US |
| Palavras-chave em inglês | Electron microscopy | en_US |
| Palavras-chave em inglês | Photochemistry | en_US |
| Palavras-chave em inglês | Physalis angulata | en_US |
