| Author | Oliveira, Luciana A. | |
| Author | Martins, Regina M. B. | |
| Author | Carneiro, Megmar A. S. | |
| Author | Teles, Sheila A. | |
| Author | Silva, Simonne A. | |
| Author | Cardoso, Divina D. P. | |
| Author | Lampe, Elisabeth | |
| Author | Yoshida, Clara F. T. | |
| Access date | 2019-08-29T12:26:48Z | |
| Available date | 2019-08-29T12:26:48Z | |
| Document date | 2002 | |
| Citation | OLIVEIRA, Luciana A. et al. Prevalence and Genotypes of GB Virus C/Hepatitis G Virus among Blood Donors in Central Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 7, p. 953-957, Oct. 2002. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/35180 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Vírus da Hepatite G | pt_BR |
| Subject in Portuguese | Vírus GB C | pt_BR |
| Subject in Portuguese | Doadores de sangue | pt_BR |
| Subject in Portuguese | Goiânia | pt_BR |
| Subject in Portuguese | Brasil Central | pt_BR |
| Title | Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1590/s0074-02762002000700005 | |
| Abstract | A survey was conducted in a blood donor population of Central Brazil aiming to investigate the prevalence of GB virus C (GBV-C)/hepatitis G virus (HGV) infection and also to analyze the virus genotypes distribution. A total of 241 voluntary blood donors were interviewed at the State Blood Bank in Goiânia, State of Goiás, Brazil. Blood samples were collected and serum samples tested for GBV-C/HGV RNA by polymerase chain reaction. Genotypes were determined by restriction fragment length polymorphism (RFLP) analysis. Seventeen samples were GBV-C/HGV RNA-positive, resulting in a prevalence of 7.1% (95% CI: 4.2-11.1). A significant trend of GBV-C/HGV RNA positivity in relation to age was observed, with the highest prevalence in donors between 29-39 years old. Ten infected individuals were characterized by reporting parenteral (30%), sexual (18%), both (6%) and intrafamiliar (6%) transmission. However, 7 (40%) GBV-C/HGV RNA-positive donors did not mention any potential transmission route. RFLP analysis revealed the presence of genotypes 1 and 2 of GBV-C/HGV; more precisely, 10 (58.9%) samples were found belonging to the 2b subtype, 4 (23.5%) to the 2a subtype, and 3 (17.6%) to genotype 1. The present data indicate an intermediate endemicity of GBV-C/HGV infection among this blood donor population, and a predominant circulation of genotype 2 (subtype 2b) in Central Brazil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Hepatitis G virus | pt_BR |
| Subject | GB virus C | pt_BR |
| Subject | Blood donors | pt_BR |
| Subject | Goiânia | pt_BR |
| Subject | Central Brazil | pt_BR |
| e-ISSN | 1678-8060 | |
