| Author | Mello, Karla Gripp Couto de | |
| Author | Mello, Fernanda C.Q. | |
| Author | Borga, Liamar | |
| Author | Rolla, Valéria Cavalcanti | |
| Author | Duarte, Rafael Silva | |
| Author | Sampaio, Elizabeth P. | |
| Author | Holland, Steven M. | |
| Author | Prevots, Rebecca | |
| Author | Dalcolmo, Margareth Maria Pretti | |
| Access date | 2019-09-16T13:37:06Z | |
| Available date | 2019-09-16T13:37:06Z | |
| Document date | 2013 | |
| Citation | MELLO, Karla Gripp Couto de et al. Clinical and Therapeutic Features of Pulmonary Nontuberculous Mycobacterial Disease, Brazil, 1993–2011. Emerging Infectious Diseases, v. 19, n. 3, p. 1-7, 2013. | pt_BR |
| ISSN | 1080-6040 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/35603 | |
| Language | eng | pt_BR |
| Publisher | Centers for Disease Control and Prevention | pt_BR |
| Rights | open access | |
| Title | Clinical and therapeutic features of pulmonary nontuberculous mycobacterial disease, Brazil, 1993-2011 | pt_BR |
| Type | Article | |
| DOI | 10.3201/eid/1903.120735 | |
| Abstract | To identify clinical and therapeutic features of pulmonary nontuberculous mycobacterial (PNTM) disease, we conducted a retrospective analysis of patients referred to the Brazilian reference center, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil, who received a diagnosis of PNTM during 1993 2011 with at least 1 respiratory culture positive for NTM. Associated conditions included bronchiectasis (21.8%), chronic obstructive pulmonary disease (20.7%), cardiovascular disease (15.5%), AIDS (9.8%), diabetes (9.8%), and hepatitis C (4.6%).Two patients had Hansen disease; 1 had Marfan syndrome. Four mycobacterial species comprised 85.6% of NTM infections: Mycobacterium kansasii, 59 cases (33.9%); M. avium complex, 53 (30.4%); M. abscessus, 23 (13.2%); and M. fortuitum, 14 (8.0%). A total of 42 (24.1%) cases were associated with rapidly growing mycobacteria. In countries with a high prevalence of tuberculosis, PNTM is likely misdiagnosed as tuberculosis, thus showing the need for improved capacity to diagnose mycobacterial disease as well as greater awareness of PNTM disease prevalence. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | National Institutes of Health. Bethesda, Maryland, USA. | pt_BR |
| Affilliation | National Institutes of Health. Bethesda, Maryland, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Nontuberculous Mycobacteria | pt_BR |
| Subject | Pulmonary Diseases | pt_BR |
| e-ISSN | 1080-6059 | |
