| Author | Lisboa, Cristiane Varella | |
| Author | Pinho, Ana Paula | |
| Author | Monteiro, Rafael Veríssimo | |
| Author | Jansen, Ana Maria | |
| Access date | 2019-09-21T19:25:49Z | |
| Available date | 2019-09-21T19:25:49Z | |
| Document date | 2007 | |
| Citation | LISBOA, Cristiane Varella et al. Trypanosoma cruzi (kinetoplastida Trypanosomatidae): Biological heterogeneity in the isolates derived from wild hosts. Experimental Parasitology, v. 116, p. 150-155, Dec. 2007. | pt_BR |
| ISSN | 0014-4894 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/35763 | |
| Language | eng | pt_BR |
| Publisher | Elsevier 12 Months | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Heternogeneidade biológica | pt_BR |
| Subject in Portuguese | Hospedeiros selvagens de mamíferos | pt_BR |
| Subject in Portuguese | Biomas brasileiros | pt_BR |
| Title | Trypanosoma cruzi (kinetoplastida Trypanosomatidae): biological heterogeneity in the isolates derived from wild hosts | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.exppara.2006.12.005 | |
| Abstract | The course of experimental infection of Swiss mice with 95 sylvatic Trypanosoma cruzi isolates included in TCI or TCII genotype was characterized. The purpose was to verify biological properties and its eventual correspondence with original host species, genotype or zymodeme. The isolates of T. cruzi were 100% infective, 55% resulted in patent parasitemia with 69% (36/52) of mortality. A meaningful biological heterogeneity was observed in both, TCI and TCII isolates. TCII isolates resulted in higher patent parasitemia 64% (38/59), in contrast to the 41% TCI infected Swiss mice (14/34). Parasitemia was not always associated to mortality. Higher biological heterogeneity was observed in T. cruzi II isolates derived from L. rosalia from the Atlantic Coastal Rain forest. TCII isolates derived from marsupials resulted in very similar infection profile in Swiss mice. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| Subject | Biological heternogeneity | pt_BR |
| Subject | Wild mammals hosts | pt_BR |
| Subject | Brazilian biomes | pt_BR |
| e-ISSN | 1090-2449 | |
| Embargo date | 2025-01-01 | |
