| Author | Bezerra, Fabrícia Salvador | |
| Author | Zancopé-Oliveira, Rosely Maria | |
| Author | Brilhante, Raimunda Sâmia Nogueira | |
| Author | Wanke, Bodo | |
| Author | Mota, Rosa Maria Salani | |
| Author | Ramos, Ana Paula Gomes | |
| Author | Ramos Jr., Alberto Novaes | |
| Author | Façanha, Mônica Cardoso | |
| Author | Leitão, Terezinha do Menino Jesus Silva | |
| Access date | 2019-09-25T13:46:45Z | |
| Available date | 2019-09-25T13:46:45Z | |
| Document date | 2013 | |
| Citation | BEZERRA, Fabrícia Salvador et al. Histoplasmin survey in HIV-positive patients: Results from an endemic area in Northeastern Brazil, v. 55, n. 4, p. 261-265, July/Aug. 2013. | pt_BR |
| ISSN | 0036-4665 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/35873 | |
| Abstract in Portuguese | Introdução: Histoplasmose disseminada ocorre com grande frequência em pacientes com aids e imunossupressão avançada no Ceará, Brasil. O objetivo deste artigo é determinar a prevalência da infecção por Histoplasma em pacientes com HIV/aids residentes em Fortaleza capital. Métodos. Testes intradérmicos com histoplasmina (fase micelial), foram realizados em 161 pacientes com CD4 ≥ 350 células/mm3. Doença recente foi estudada por imunodifusão em 76 desses indivíduos. Resultados. Reagiram à histoplasmina, 11,8% dos pacientes e à imunodifusão para Histoplasma: 2,63%. A presença da árvore mangueira (Mangifera indica)
na vizinhança (OR = 2,870; IC 95% = 1,081-7,617; p = 0,040), atividade com o solo no passado (OR = 2,834; IC 95% = 1,045-7,687, p = 0,045) e visitar sítio no passado (OR = 3,869; IC 95% = 1,189-12,591; p = 0,033); foram significativamente associados com positividade para o teste. Conclusões: Pacientes com HIV que vivem em Fortaleza apresentam uma prevalência expressiva de infecção por Histoplasma. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Universidade de São Paulo | pt_BR |
| Rights | open access | pt_BR |
| Title | Histoplasmin survey in HIV-positive patients: Results from an endemic area in Northeastern Brazil | pt_BR |
| Alternative title | Inquérito com histoplasmina em pacientes HIV positivos: resultados de uma área endêmica no Nordeste do Brasil | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/S0036-46652013000400007 | |
| Abstract | Background. Disseminated histoplasmosis is common in AIDS patients with advanced immunosuppression in Ceará, Northeastern Brazil. The goal of this study was to determine the prevalence of Histoplasma infection in patients with HIV/AIDS living in Fortaleza, the capital of Ceará. Methods. Intradermal tests with histoplasmin (mycelial phase) were performed in 161 HIV patients with CD4 ≥ 350 cells/mm3 . Evidence of recent illness was evaluated with immunodiffusion (ID) tests in 76 of these individuals. Results. A total of 11.8% of patients reacted to histoplasmin and 2.63% had ID test positive to Histoplasma. The presence of mango trees
(Mangifera indica) in the patient neighborhood (OR = 2.870; 95% CI = 1.081-7.617; p = 0.040) and past activity involving soil (OR = 2.834; 95% CI = 1.045-7.687; p = 0.045) or visits to a farm (OR = 3.869; 95% CI = 1.189-12.591; p = 0.033) were significantly associated with Histoplasma infection. Conclusions. Patients with HIV living in Fortaleza have an expressive prevalence of infection with Histoplasma. | pt_BR |
| Affilliation | Federal University of Ceará. School of Medicine. Department of Community Health. Fortaleza, CE, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Federal University of Ceará. Medical Mycology Research Center. Fortaleza, CE, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Federal University of Ceará. School of Medicine. Department of Community Health. Fortaleza, CE, Brazil. | pt_BR |
| Affilliation | Municipal Health Department. Center of Medical Specialties José de Alencar. Fortaleza, CE, Brazil. | pt_BR |
| Affilliation | Federal University of Ceará. School of Medicine. Department of Community Health. Fortaleza, CE, Brazil. | pt_BR |
| Affilliation | Federal University of Ceará. School of Medicine. Department of Community Health. Fortaleza, CE, Brazil. | pt_BR |
| Affilliation | Federal University of Ceará. School of Medicine. Department of Community Health. Fortaleza, CE, Brazil. | pt_BR |
| Subject | Histoplasmosis | pt_BR |
| Subject | Histoplasmin | pt_BR |
| Subject | Epidemiology | pt_BR |
| Subject | AIDS | pt_BR |
| Subject | HIV | pt_BR |
| e-ISSN | 1678-9946 | |
