| Author | Silva, J. L. | |
| Author | Oliveira, V. V. G. | |
| Author | Silva, L. A. M. T. | |
| Author | Silva, R. P. e. | |
| Author | Alves, L. C. | |
| Author | Cavalcanti, M. P. | |
| Author | Silva Júnior, V. A. | |
| Access date | 2019-09-26T14:35:13Z | |
| Available date | 2019-09-26T14:35:13Z | |
| Document date | 2019 | |
| Citation | SILVA, J. L. et al. Evaluation of Serum Biochemical Parameters, Structural Changes, Immunohistochemistry and Parasite Load in the Urinary System of Dogs Infected Naturally by Leishmania infantum. Journal of Comparative Pathology, v. 167, p. 26-31, Feb. 2019. | pt_BR |
| ISSN | 0021-9975 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/35926 | |
| Language | eng | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Evaluation of Serum Biochemical Parameters, Structural Changes, Immunohistochemistry and Parasite Load in the Urinary System of Dogs Infected Naturally by Leishmania infantum | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.jcpa.2018.11.007 | |
| Abstract | The aim of this study was to evaluate the histopathological changes in the urinary system and their correlation with serum biochemical parameters, parasite load and immunodetection of amastigotes in 30 dogs infected naturally by Leishmania infantum. The major histological changes were glomerulonephritis and interstitial nephritis. Serum biochemistry demonstrated that the dogs had progressive loss of renal function. L. infantum amastigotes were detected immunohistochemically in all parts of the urinary system, except the ureters. There was a correlation between parasite load, severity of histopathological changes and immunodetection of the parasites, but parasite load was not correlated with the serum biochemical parameters evaluated. | pt_BR |
| Affilliation | Universidade Federal Rural de Pernambuco. Departamento de Morfologia e Fisiologia Animal. Recife, PE, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Pernambuco. Centro Acadêmico de Vitória. Vitória de Santo Antão, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife PE, Brasil. | pt_BR |
| Affilliation | Universidade Federal Rural de Pernambuco. Departamento de Medicina Veterinária. Recife, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife PE, Brasil. | pt_BR |
| Affilliation | Universidade Federal Rural de Pernambuco. Departamento de Medicina Veterinária. Recife, PE, Brasil. | pt_BR |
| Subject | Dog | pt_BR |
| Subject | Immunohistochemistry | pt_BR |
| Subject | Urinary system | pt_BR |
| Subject | Visceral leishmaniosis | pt_BR |
| DeCS | Animais | pt_BR |
| DeCS | Doenças do Cão | pt_BR |
| DeCS | Metabolismo | pt_BR |
| DeCS | Parasitologia | pt_BR |
| DeCS | Patologia | pt_BR |
| DeCS | Cães | pt_BR |
| DeCS | Imuno-Histoquímica | pt_BR |
| DeCS | Leishmania infantum | pt_BR |
| DeCS | Leishmaniose Visceral | pt_BR |
| DeCS | Veterinária | pt_BR |
| DeCS | Masculino | pt_BR |
| DeCS | Carga Parasitária | pt_BR |
| DeCS | Infecções Urinárias | pt_BR |
| Embargo date | 2050-01-01 | |
