| Author | Nery, Joilda Silva | pt_BR |
| Author | Ramond, Anna | pt_BR |
| Author | Pescarini, Júlia Moreira | pt_BR |
| Author | Alves, André | pt_BR |
| Author | Strina, Agostino | pt_BR |
| Author | Ichihara, Maria Yury Travassos | pt_BR |
| Author | Penna, Maria Lucia Fernandes | pt_BR |
| Author | Smeeth, Liam | pt_BR |
| Author | Rodrigues, Laura Cunha | pt_BR |
| Author | Barreto, Mauricio Lima | pt_BR |
| Author | Brickley, Elizabeth B. | pt_BR |
| Author | Penna, Gerson Oliveira | pt_BR |
| Access date | 2019-10-01T13:41:13Z | |
| Available date | 2019-10-01T13:41:13Z | |
| Document date | 2019 | |
| Citation | NERY, Joilda Silva et al. Socioeconomic determinants of leprosy new case detection in the 100 Million Brazilian Cohort: a population-based linkage study. Lancet Global Health, v. 7, n. 9, p. 1-11, 2019. | pt_BR |
| ISSN | 2214-109X | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/36031 | |
| Sponsorship | Medical Research Council, Wellcome Trust, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brazil), the Conselho Nacional das Fundações Estaduais de Amparo à Pesquisa, Economic and Social Research Council, Biotechnology and Biological Sciences Research Council, Conselho Nacional de Desenvolvimento Científico e Tecnológico, and Fundação de Apoio à Pesquisa do Distrito Federal. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Hanseniase | pt_BR |
| Subject in Portuguese | Fatores de risco | pt_BR |
| Subject in Portuguese | Condições Socioeconómicas | pt_BR |
| Subject in Portuguese | População Carente | pt_BR |
| Subject in Portuguese | Humanos | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Title | Socioeconomic determinants of leprosy new case detection in the 100 Million Brazilian Cohort: a population-based linkage study | en |
| Type | Article | pt_BR |
| DOI | 10.1016/S2214-109X(19)30260-8 | |
| Abstract | Although leprosy is recognised as a disease of poverty, there is little evidence on the specific socioeconomic factors associated with disease risk. To inform targeted strategies for disease elimination, we investigated socioeconomic markers of leprosy risk in Brazil. Methods Socioeconomic data from the 100 Million Brazilian Cohort were linked to the Brazilian national disease
registry (Sistema de Informação de Agravos de Notificação) for leprosy from Jan 1, 2007, to Dec 31, 2014. Using
Poisson regression, we assessed the association of socioeconomic factors with risk of incident leprosy in the full
cohort and in children (aged 0–15 years), by leprosy subtype and region of residence.
Findings In an analysis of 23 899 942 individuals including 18 518 patients with leprosy, increased levels of deprivation
were associated with an increased risk of leprosy in Brazil. Directions of effect were consistent in children younger
than 15 years and across disease subtypes. Individuals residing in regions with the highest poverty in the country
(central-west, north, and northeast regions) had a risk of leprosy incidence five-to-eight times greater than did other
individuals. Decreased levels of income and education and factors reflecting unfavourable living conditions were
associated with an up to two-times increase in leprosy incidence (incidence rate ratio 1·46, 95% CI 1·32–1·62, for
lowest vs highest quartile of income per capita; 2·09, 95% CI 1·62–2·72, for lowest vs highest level of education).
Interpretation Within the poorest half of the Brazilian population, the most deprived individuals have the greatest risk
of leprosy. Strategies focusing on early detection and treatment in the poorest populations could contribute
substantially to global disease control. | en |
| Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil. | pt_BR |
| Affilliation | London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK. | pt_BR |
| Affilliation | Federal University Fluminense. Epidemiology and Biostatistics Department. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Federal University Fluminense. Epidemiology and Biostatistics Department. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Federal University Fluminense. Epidemiology and Biostatistics Department. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Federal University Fluminense. Epidemiology and Biostatistics Department. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | University of Brasília. Tropical Medicine Centre. Brasília, DF, Brazil / Oswaldo Cruz Foundation. School of Goverment Brasília. Brasília, DF, Brazil. | pt_BR |
| Affilliation | London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK. | pt_BR |
| Affilliation | London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para Saúde. Salvador, BA, Brasil. | pt_BR |
| Affilliation | London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK. | pt_BR |
| Affilliation | Federal University Fluminense. Epidemiology and Biostatistics Department. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Subject | Leprosy | en |
| Subject | Risk Factors | en |
| Subject | Social Class | en |
| Subject | Vulnerable Populations | en |
| Subject | Humans | en |
| Subject | Brazil | en |
| e-ISSN | 2214-109X | |
| xmlui.metadata.dc.subject.ods | 01 Erradicação da pobreza | |
| xmlui.metadata.dc.subject.ods | 10 Redução das desigualdades | |
