| Author | Ribeiro, Luciano Corrêa | |
| Author | Wanke, Bodo | |
| Author | Silva, Manuela da | |
| Author | Dias, Luciana Basili | |
| Author | Mello, Renato | |
| Author | Canavarros, Fernando Artur Pena Borges | |
| Author | Leite-Jr, Diniz Pereira | |
| Author | Hahn, Rosane Christine | |
| Access date | 2019-10-22T13:02:26Z | |
| Available date | 2019-10-22T13:02:26Z | |
| Document date | 2012 | |
| Citation | RIBEIRO, Luciano Corrêa et al. Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis. Mycopathologia, v. 173, p. 187-192, 2012. | pt_BR |
| ISSN | 0301-486X | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/36627 | |
| Language | eng | pt_BR |
| Publisher | Springer Verlag | pt_BR |
| Rights | open access | pt_BR |
| Title | Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1007/s11046-011-9472-0 | |
| Abstract | We identified the etiological agents responsible for two fatal cases of rhinocerebral mucormycosis with the classical risk factor for uncontrolled type II diabetes mellitus. Their initial symptoms did not point immediately to the suspicion of mucormycosis. Case 1, caused by Rhizopus microsporus var. oligosporus, was a 52-year-old man who presented with a painful pimple on his nose, which evolved with swelling, erythema, and a central
pustule on his right hemiface suspected to be cellulitis. After 7 days of antibiotic treatment, the patient worsened with signs of sepsis and the lesion evolved to necrosis involving all his right face. Case 2, caused
by Rhizopus microsporus var. rhizopodiformis, was a 57-year-old woman placed on continuous therapy with
azathioprine and corticoids after a renal transplant due to chronic arterial hypertension and uncontrolled type
II diabetes mellitus. Because she was suspected to have sepsis, the patient was treated with broadspectrum antibiotics and mechanical ventilation, yet she deteriorated. Because Candida spp. were isolated from urine and a BAL, she was treated with fluconazole for 10 days, then substituted by caspofungin. Two weeks later, she presented with exophthalmus of the left eye that was surrounded by a large inflammatory and necrotic area. Both patients were the diagnosed with mucormycosis via direct microscopy of necrotic material prior to their death. | pt_BR |
| Affilliation | University of Mato Grosso. Faculty of Medicine. Mycology Laboratory. Cuiabá, MT, Brazil / Infectious and Tropical Diseases Centre of Mato Grosso. Cuiabá, MT, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Programa de Pós-Graduação em Vigilância Sanitária. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | University of Mato Grosso. Faculty of Medicine. Mycology Laboratory. Cuiabá, MT, Brazil. | pt_BR |
| Affilliation | Santa Rosa Hospital. Cuiabá, MT, Brazil. | pt_BR |
| Affilliation | Santa Rosa Hospital. Cuiabá, MT, Brazil. | pt_BR |
| Affilliation | Infectious and Tropical Diseases Centre of Mato Grosso. Cuiabá, MT, Brazil. | pt_BR |
| Affilliation | University of Mato Grosso. Faculty of Medicine. Mycology Laboratory. Cuiabá, MT, Brazil. | pt_BR |
| Subject | Mucormycosis | pt_BR |
| Subject | Brazil | pt_BR |
| Subject | Rhizopus microsporus var. oligosporus | pt_BR |
| Subject | Rhizopus microsporus var. rhizopodiformis | pt_BR |
| e-ISSN | 1573-0832 | |
| Embargo date | 2020-10-22 | |
