| Author | Mendes, Leonardo Diniz | |
| Author | Devalle, Sylvie | |
| Author | Niel, Christian | |
| Access date | 2019-10-26T18:04:18Z | |
| Available date | 2019-10-26T18:04:18Z | |
| Document date | 2004 | |
| Citation | MENDES, Leonardo Diniz; DEVALLE, Sylvie; NIEL, Christian. Genomic Characterization of a Brazilian TT Virus Isolate Closely Related to SEN Virus-F. Memórias do Insituto Oswaldo Cruz, Rio de Janeiro, v. 99. n. 3, p. 301-306, May 2004. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/36722 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Hepatite | pt_BR |
| Subject in Portuguese | Vírus da imunodeficiência humana tipo 1 | pt_BR |
| Subject in Portuguese | Sequenciamento de nucleotídeos | pt_BR |
| Subject in Portuguese | Torque teno virus | pt_BR |
| Title | Genomic Characterization of a Brazilian TT Virus Isolate Closely Related to SEN Virus-F | pt_BR |
| Type | Article | |
| DOI | 10.1590/S0074-02762004000300011 | |
| Abstract | SEN virus (SENV) is a circular, single stranded DNA virus that has been first characterized in the serum of a human immunodeficiency virus type 1 (HIV-1)-infected patient. Eight genotypes of SENV (A-H) have been identified and further recognized as variants of TT virus (TTV) in the family Circoviridae. Here we describe the first genomic characterization of a SENV isolate (5-A) from South America. Using ‘universal’ primers, able to amplify most, if not all, TTV/SENV genotypes, a segment of > 3 kb was amplified by polymerase chain reaction from the serum of an HIV-1 infected patient. The amplicon was cloned and a 3087-nucleotide sequence was determined, that showed a high (85%) homology with the sequence of the Italian isolate SENV-F. Proteins encoded by open reading frames (ORFs) 1 to 4 consisted of 758, 129, 276, and 267 amino acids, respectively. By phylogenetic analysis, isolate 5-A was classified into TTV genotype 19 (phylogenetic group 3), together with SENV-F and TTV isolate SAa-38. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Hepatitis | pt_BR |
| Subject | Human immunodeficiency virus type 1 | pt_BR |
| Subject | Nucleotide sequencing | pt_BR |
| Subject | Open reading frames 1-4 | pt_BR |
| Subject | SEN virus-F | pt_BR |
| Subject | TT virus | pt_BR |
| e-ISSN | 1678-8060 | |
