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AutorCalderon, Roger I.
AutorArriaga Gutiérrez, María Belen
AutorLopez, Kattya
AutorBarreda, Nadia N.
AutorSanabria, Oswaldo M.
AutorFróes Neto, José F.
AutorAraújo, Davi Neri
AutorLecca, Leonid
AutorAndrade, Bruno de Bezerril
Fecha de acceso2019-10-29T12:12:29Z
Fecha de disponibilización2019-10-29T12:12:29Z
Fecha de publicación2019
ReferenciaCALDERON, Roger I. et al. High prevalence and heterogeneity of Dysglycemia in patients with tuberculosis from Peru: a prospective cohort study. BMC Infectious Diseases, v. 19, p. 1-11, 2019.pt_BR
ISSN1471-2334pt_BR
URIhttps://www.arca.fiocruz.br/handle/icict/36726
PromociónConsejo Nacional de Ciencia, Tecnología e Innovación Tecnológica (CONCYTEC-Peru) / Fondo Nacional de Desarrollo Científico, Tecnológico y de Innovación Tecnológica (FONDECYT, Convenio 175–2015). The work from BBA was supported by intramural research program from FIOCRUZ, by the National Institutes of Health (U01AI115940 and U01AI069923) and by the Departamento de Ciência e Tecnologia (DECIT) - Secretaria de Ciência e Tecnologia (SCTIE) – Ministério da Saúde (MS), Brazil (25029.000507/2013–07). MBA receives a fellowship from the Fundação de Amparo à Pesquisa da Bahia (FAPESB). BBA is a senior scientist from the Conselho Nacional de Desenvolvimento Científico e Tecnológico.pt_BR
Idiomaengpt_BR
EditorBMCpt_BR
Derechos de autoropen accesspt_BR
Palabras clave en PortuguésDiabetes mellituspt_BR
Palabras clave en PortuguésPré-diabetespt_BR
Palabras clave en PortuguésTuberculosept_BR
Palabras clave en PortuguésComorbidadept_BR
Palabras clave en PortuguésPrevalênciapt_BR
TítuloHigh prevalence and heterogeneity of Dysglycemia in patients with tuberculosis from Peru: a prospective cohort studypt_BR
Tipo del documentoArticlept_BR
DOI10.1186/s12879-019-4416-2
Resumen en InglésThe accuracy of different laboratory tests for diagnosis of diabetes mellitus (DM) and prediabetes (preDM) in populations exposed to tuberculosis (TB) remains poorly understood. Here, we examined the prevalence of DM and preDM in TB affected people in Lima, Peru. Methods: A prospective cohort study of patients affected TB and their household contacts (HHC), was conducted between February and November 2017 in Lima, Peru. Fasting plasma glucose (FPG), HbA1c and oral glucose tolerance test (OGTT) were used to detect DM and preDM in a prospective cohort of TB patients (n = 136) and household contacts (n = 138). Diagnostic performance of the laboratory tests was analyzed. Potential effects of sociodemographic and clinical factors on detection of dysglycemia were analyzed. Results: In TB patients, prevalence of DM and preDM was 13.97 and 30.88% respectively. Lower prevalence of both DM (6.52%) and preDM (28.99%) were observed in contacts. FPG, HbA1c and OGTT had poor agreement in detection of preDM in either TB cases or contacts. TB-DM patients had substantially lower hemoglobin levels, which resulted in low accuracy of HbA1c-based diagnosis. Classic sociodemographic and clinical characteristics were not different between TB patients with or without dysglycemia. Conclusion: High prevalence of DM and preDM was found in both TB patients and contacts in Lima. Anemia was strongly associated with TB-DM, which directly affected the diagnostic performance of HbA1c in such population.pt_BR
AfiliaciónSocios en Salud Sucursal Peru. Lima, Peru / Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Rio de Janeiro, RJ, Brasil.pt_BR
AfiliaciónUniversidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Fundação José Silveira. Instituto Brasileiro para Investigação da Tuberculose. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Fundação José Silveira. Multinational Organization Network Sponsoring Translational and Epidemiological Research Initiative. Salvador, BA, Brazil.pt_BR
AfiliaciónSocios en Salud Sucursal Peru. Lima, Peru.pt_BR
AfiliaciónSocios en Salud Sucursal Peru. Lima, Peru.pt_BR
AfiliaciónSocios en Salud Sucursal Peru. Lima, Peru.pt_BR
AfiliaciónFundação José Silveira. Multinational Organization Network Sponsoring Translational and Epidemiological Research Initiative. Salvador, BA, Brazil / Faculdade de Tecnologia e Ciências. Curso de Medicina. Salvador, BA, Brasil.pt_BR
AfiliaciónUniversidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Fundação José Silveira. Multinational Organization Network Sponsoring Translational and Epidemiological Research Initiative. Salvador, BA, Brazil.pt_BR
AfiliaciónUniversidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Harvard Medical School / Department of Global Health and Social Medicine. Boston, MA, USA.pt_BR
AfiliaciónSocios en Salud Sucursal Peru. Lima, Peru / Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Rio de Janeiro, RJ, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Fundação José Silveira. Instituto Brasileiro para Investigação da Tuberculose. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Fundação José Silveira. Multinational Organization Network Sponsoring Translational and Epidemiological Research Initiative. Salvador, BA, Brasil / Faculdade de Tecnologia e Ciências. Curso de Medicina. Salvador, BA, Brasil / Universidade de Salvador. Salvador, BA, Brasil /Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil.pt_BR
Palavras clave en InglêsDiabetes mellituspt_BR
Palavras clave en InglêsPrediabetespt_BR
Palavras clave en InglêsTuberculosispt_BR
Palavras clave en InglêsComorbiditypt_BR
Palavras clave en InglêsPrevalencept_BR


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