| Author | Facchinetti, Victor | |
| Author | Gomes, Claudia R. B. | |
| Author | Souza, Marcus Vinícius Nora de | |
| Author | Vasconcelos, Thatyana Rocha Alves | |
| Access date | 2019-12-10T13:14:07Z | |
| Available date | 2019-12-10T13:14:07Z | |
| Document date | 2012 | |
| Citation | FACCHINETTI, Victor et al. Perspectives on the Development of Novel Potentially Active Quinolones Against Tuberculosis and Cancer. Mini-Reviews in Medicinal Chemistry, v. 12, p. 866-874, 2012. | pt_BR |
| ISSN | 1389-5575 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/37741 | |
| Language | eng | pt_BR |
| Publisher | Mini-Reviews in Medicinal Chemistry | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Perspectives on the Development of Novel Potentially Active Quinolones Against Tuberculosis and Cancer | pt_BR |
| Type | Article | |
| DOI | 10.2174/138955712800959099 | pt_BR |
| Abstract | Quinolones and its derivatives comprise an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as antibacterial, antitumor, antiviral, anti-ischemic, antiparasitic and anxiolytic.
Persistent efforts have been made over the years to develop novel congeners with superior biological activities and minimal potential for undesirable side-effects. The present review aims to highlight some recent discoveries on the development of novel quinolone-based compounds with potential antitubercular and anticancer activity. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Rio de Janeiro, RJ, Brasil / Universidade Federal Fluminense. Instituto de Química. Departamento de Química Orgânica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal Fluminense. Instituto de Química. Departamento de Química Orgânica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Biological Activity | pt_BR |
| Subject | Cancer | pt_BR |
| Subject | Drugs | pt_BR |
| Subject | Quinolones | pt_BR |
| Subject | Tuberculosis | pt_BR |
