| Author | Fonseca, Erica L. | |
| Author | Vieira, Verônica V. | |
| Author | Cipriano, Rosângela | |
| Author | Vicente, Ana C. P. | |
| Access date | 2019-12-12T11:24:08Z | |
| Available date | 2019-12-12T11:24:08Z | |
| Document date | 2005 | |
| Citation | FONSECA, Érica L. et al. Class 1 integrons in Pseudomonas aeruginosa isolates from clinical settings in Amazon region, Brazil. FEMS Immunology and Medical Microbiology, v. 44, p. 303-309, 2005. | pt_BR |
| ISSN | 0928-8244 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/37885 | |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Pseudomonas aeruginosa | pt_BR |
| Subject in Portuguese | Configuração clínica da Amazônia | pt_BR |
| Subject in Portuguese | Integrons Classe 1 | pt_BR |
| Title | Class 1 integrons in Pseudomonas aeruginosa isolates from clinical settings in Amazon region, Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.femsim.2005.01.004 | |
| Abstract | A hundred and six Pseudomonas aeruginosa isolates from clinical cases were screened using PCR for the presence of integrons and associated resistance gene cassettes. Forty-four isolates harboured class 1 integrons (41.5%), of which 29 isolates (66%) also carried gene cassettes. The aacA gene was most frequently found within class 1 integrons (69%), followed by blaOXA family genes (52%). From class 1 integron-positive strains, we detected a total of 15 isolates (34%) carrying no gene cassettes. Restriction fragment-length polymorphism analysis of the integrons variable region revealed some identical structures, as well as distinct profiles indicating heterogeneity among these cassette regions. Multiresistance was observed in 71% of isolates, nevertheless no strong correlation was observed between integron presence and multiresistance. This is the first report showing class 1 integron prevalence and gene cassette content in P. aeruginosa isolates from clinical settings in the Brazilian Amazon. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Genética. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Microbiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Maranhão. São Luis, MA, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Genética. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Class 1 integron | pt_BR |
| Subject | Pseudomonas aeruginosa | pt_BR |
| Subject | Amazon clinical setting | pt_BR |
| e-ISSN | 1574-695X | |
