| Author | Pacheco, Raquel S. | |
| Author | Brito, Célia M. Marques de | |
| Author | Sarquis, Otilia | |
| Author | Pires, Marize Q. | |
| Author | Pereira, José Borges | |
| Author | Lima, Marli M. | |
| Access date | 2019-12-17T14:57:10Z | |
| Available date | 2019-12-17T14:57:10Z | |
| Document date | 2005 | |
| Citation | PACHECO, Raquel S. et al. Genetic Heterogeneity in Trypanosoma cruzi Strains From Naturally Infected Triatomine Vectors in Northeastern Brazil: Epidemiological Implications. Biochemical Genetics, v. 43, n. 9/10, p. 519-530, 2005. | pt_BR |
| ISSN | 0006-2928 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/38654 | |
| Language | eng | pt_BR |
| Publisher | Springer | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Doença de Chagas | pt_BR |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Epemiologia molecular | pt_BR |
| Subject in Portuguese | Triatomíneos | pt_BR |
| Subject in Portuguese | Eletroforese enzimática multifoco | pt_BR |
| Subject in Portuguese | Polimórfico amplificado aleatoriamente | pt_BR |
| Title | Genetic heterogeneity in Trypanosoma cruzi strains from naturally infected triatomine vectors in northeastern Brazil: epidemiological implications | pt_BR |
| Type | Article | |
| DOI | 10.1007/s10528-005-8168-x | |
| Abstract | Eighteen Trypanosoma cruzi strains isolated from naturally infected triatomines were studied genetically. The majority of the strains were from Triatoma brasiliensis, the principal vector of Chagas disease in the northeast of Brazil. Multilocus enzyme electrophoresis (MLEE) and randomly amplified polymorphic DNA (RAPD) analyses were used to investigate the genotypic diversity and the spread of the T. cruzi genotypes in different environments. MLEE clearly distinguished two distinct isoenzyme profiles, and RAPD analysis revealed 10 different genotypes circulating in rural areas. The strains could be typed as isoenzyme variants of the T. cruzi principal zymodeme Z1 (T. cruzi I). An effective program of epidemiological vigilance is required to prevent the spread of T. cruzi I strains into human dwellings. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pùblica Sergio Arouca. Departamento de Ciências Biológicas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Chagas Disease | pt_BR |
| Subject | MLEE | pt_BR |
| Subject | Molecular epidemiology | pt_BR |
| Subject | RAPD | pt_BR |
| Subject | Triatomines | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| e-ISSN | 1573-4927 | |
| Embargo date | 2025-01-01 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
