Author | Vieira, Jessica Manya B. D. | |
Author | Boente, Renata F. | |
Author | Miranda, Karla Rodrigues | |
Author | Avelar, Kátia E. S. | |
Author | Domingues, Regina M. C. P. | |
Author | Ferreira, Maria Candida de S. | |
Access date | 2020-02-06T11:51:40Z | |
Available date | 2020-02-06T11:51:40Z | |
Document date | 2006 | |
Citation | VIEIRA, Jessica Manya B. D. et al. Decreased Susceptibility to Nitroimidazoles Among Bacteroides Species in Brazil. Current Microbiology, v. 52, p. 27-32, 2006. | pt_BR |
ISSN | 0343-8651 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/39760 | |
Language | eng | pt_BR |
Publisher | Springer | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Nitroimidazóis | pt_BR |
Subject in Portuguese | Espécies de bacteróides | pt_BR |
Subject in Portuguese | Brasil | pt_BR |
Title | Decreased susceptibility to nitroimidazoles among Bacteroides species in Brazil | pt_BR |
Type | Article | pt_BR |
DOI | 10.1007/s00284-005-0068-0 | |
Abstract | In this study, 197 strains of Bacteroides genus from different species and origins were evaluated with regard to their susceptibility to 5-nitroimidazoles (5-Ni)-such as tinidazole, ornidazole, and metronidazole-using the agar dilution method. The presence of nim genes was also investigated by polymerase chain reaction. It was found that 5.6% of Bacteroides strains among all origins showed decreased susceptibility (minimum inhibitory concentrations varying from 4 to 16 microg/ml) to at least one of the imidazoles studied without any known nim gene associate. Also, we detected one strain isolated from a polluted aquatic environment in which one nim gene was found and characterized as nim B using restriction fragment length polymorphism and sequencing. Hence, resistance to 5-Ni should be monitored closely because they constitute, among few drugs, the ones quite effective in treating Bacteroides infections. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Prof. Paulo de Góes. Departamento de Microbiologia Médica. Laboratório de Biologia de Anaeróbios. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Prof. Paulo de Góes. Departamento de Microbiologia Médica. Laboratório de Biologia de Anaeróbios. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Prof. Paulo de Góes. Departamento de Microbiologia Médica. Laboratório de Biologia de Anaeróbios. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bacteriologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Prof. Paulo de Góes. Departamento de Microbiologia Médica. Laboratório de Biologia de Anaeróbios. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Prof. Paulo de Góes. Departamento de Microbiologia Médica. Laboratório de Biologia de Anaeróbios. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Nitroimidazoles | pt_BR |
Subject | Bacteroides Species | pt_BR |
Subject | Brazil | pt_BR |
e-ISSN | 1432-0991 | |
Embargo date | 2025-01-01 | |