| Author | Mosimann, Ana Luiza Pamplona | |
| Author | Bordignon, Juliano | |
| Author | Mazzarotto, Giovanny Augusto Camacho Antevere | |
| Author | Motta, Maria Cristina Machado | |
| Author | Hoffmann, Federico | |
| Author | Santos, Claudia Nunes Duarte dos | |
| Access date | 2020-02-10T20:03:33Z | |
| Available date | 2020-02-10T20:03:33Z | |
| Document date | 2011 | |
| Citation | MOSIMANN, Ana Luiza Pamplona et al. Genetic and biological characterization of a densovirus isolate that affects dengue virus infection. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 106, n. 3, p. 285-292, 2011. | pt_BR |
| ISSN | 1678-8060 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/39822 | |
| Language | por | pt_BR |
| Publisher | Fiocruz/IOC | pt_BR |
| Rights | open access | pt_BR |
| Title | Genetic and biological characterization of a densovirus isolate that affects dengue virus infection | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/s0074-02762011000300006 | |
| Abstract | Brevidensoviruses have an encapsidated, single-stranded DNA genome that predominantly has a negative polarity. In recent years, they have received particular attention due to their potential role in the biological control of pathogenic arboviruses and to their unnoticed presence in cell cultures as contaminants. In addition, brevidensoviruses may also be useful as viral vectors. This study describes the first genetic and biological characterization of a mosquito densovirus that was isolated in Brazil; moreover, we examined the phylogenetic relationship between this isolate and the other brevidensoviruses. We further demonstrate that this densovirus has the potential to be used to biologically control dengue virus (DENV) infection with in vitro co-infection experiments. The present study provides evidence that this densovirus isolate is a fast-spreading virus that affects cell growth and DENV infection. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Department of Biochemistry and Molecular Biology. Mississippi State University. Mississippi State, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | pt_BR |
| Subject | Biological control | pt_BR |
| Subject | Dengue Virus | pt_BR |
| Subject in Spanish | Virus del Dengue | pt_BR |
| DeCS | Densovirus | pt_BR |
| DeCS | Densovirinae | pt_BR |
| DeCS | Vírus da Dengue | pt_BR |
| e-ISSN | 1678-8060 | |
