Author | Freitas, Priscilla Ramos | |
Author | Araújo, Ana Carolina Justino de | |
Author | Barbosa, Cristina Rodrigues dos Santos | |
Author | Muniz, Débora Feitosa | |
Author | Silva, Ana Cristina Albuquerque da | |
Author | Rocha, Janaína Esmeraldo | |
Author | Tintino, Cícera Datiane de Morais Oliveira | |
Author | Ribeiro Filho, Jaime | |
Author | Silva, Luiz Everson da | |
Author | Confortin, Camila | |
Author | Amaral, Wanderlei do | |
Author | Deschamps, Cícero | |
Author | Barbosa Filho, José Maria | |
Author | Lima, Natanael Teles Ramos de | |
Author | Tintino, Saulo Relison | |
Author | Coutinho, Henrique Douglas Melo | |
Access date | 2020-02-11T12:16:31Z | |
Available date | 2020-02-11T12:16:31Z | |
Document date | 2020 | |
Citation | FREITAS, Priscilla Ramos et al. GC-MS-FID and potentiation of the antibiotic activity of the essential oil of Baccharis reticulata (ruiz & pav.) pers. and α-pinene. Industrial Crops and Products, v. 145, p. 1-5, 2020. | pt_BR |
ISSN | 0926-6690 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/39839 | |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Baccharis reticulado | pt_BR |
Subject in Portuguese | α-pineno | pt_BR |
Subject in Portuguese | Pseudomonas aeruginosa | pt_BR |
Subject in Portuguese | Antibióticos | pt_BR |
Title | GC-MS-FID and potentiation of the antibiotic activity of the essential oil of Baccharis reticulata (ruiz & pav.) pers. and α-pinene | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.indcrop.2020.112106 | pt_BR |
Abstract | The genus Baccharis (Asteraceae) demonstrated the presence of compounds with antibacterial, antifungal and
antioxidant activities. Because of the increasing rates of antimicrobial resistance, adequate treatment of infections
caused by Gram-negative bacteria has become challenging. The objective of the present study was evaluate
the antibacterial and antibiotic-modifying activity of the essential oil obtained from Baccharis reticulata (Ruiz &
Pav.) Pers. and the compound α-pinene against Pseudomonas aeruginosa and other multiresistant bacteria. An
analysis by gas chromatography associated with mass spectrometry (GC/MS) revealed the presence of dilapiol
(33.8 %), α-pinene (31.7 %) and β-pinene (9.4 %) as major components of the oil. The determination of the
Minimum Inhibitory Concentration (MIC) revealed that the oil has antibacterial activity against S. aureus only.
However, the oil potentiated the norfloxacin and gentamicin against all strains evaluated. Also, α-pinene increased
the activity of norfloxacin against E. coli, as well as potentiated the activity of norfloxacin and gentamicin
against S. aureus. Therefore, the authors conclude that the essential oil of B. reticulata, as well as the
compound α-pinene, have antibacterial and antibiotic-modulating activities that make them useful in the development
of new weapons against bacterial resistance. | pt_BR |
Affilliation | Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil. | pt_BR |
Affilliation | Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil. | pt_BR |
Affilliation | Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil. | pt_BR |
Affilliation | Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil. | pt_BR |
Affilliation | Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil. | pt_BR |
Affilliation | Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil. | pt_BR |
Affilliation | Federal University of Pernambuco. Department of Antibiotics. Recife, PE, Brazil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
Affilliation | Federal University of Paraná. Post Graduation Course of Sustainable Territorial Development. Matinhos, PR, Brazil. | pt_BR |
Affilliation | Federal University of Paraná. Post Graduation Course of Sustainable Territorial Development. Matinhos, PR, Brazil. | pt_BR |
Affilliation | Federal University of Paraná. Department of Chemical Technology. Curitiba, PR, Brazil. | pt_BR |
Affilliation | Federal University of Paraná. Post Graduation Course of Agronomy. Curitiba, PR, Brazil. | pt_BR |
Affilliation | Federal University of Paraiba. Department of Pharmacy. João Pessoa, PB, Brazil. | pt_BR |
Affilliation | Federal University of Paraiba. Department of Pharmacy. João Pessoa, PB, Brazil. | pt_BR |
Affilliation | Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil. | pt_BR |
Affilliation | Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil. | pt_BR |
Subject | Baccharis reticulate | pt_BR |
Subject | α-pinene | pt_BR |
Subject | Pseudomonas aeruginosa | pt_BR |
Subject | Antibiotics | pt_BR |