| Author | Reifur, Larissa | |
| Author | Garcia-Silva, Maria Rosa | |
| Author | Poubel, Saloê Bispo | |
| Author | Alves, Lysangela Ronalte | |
| Author | Arauco, Paulo | |
| Author | Buiar, Diane Kelly | |
| Author | Goldenberg, Samuel | |
| Author | Cayota, Alfonso | |
| Author | Dallagiovanna, Bruno | |
| Access date | 2020-02-11T15:01:02Z | |
| Available date | 2020-02-11T15:01:02Z | |
| Document date | 2012 | |
| Citation | REIFUR, Larissa et al. Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.107, n. 6, p. 816–819, Sept. 2012. | pt_BR |
| ISSN | 1678-8060 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/39854 | |
| Language | por | pt_BR |
| Publisher | Fiocruz/IOC | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | TRNA | pt_BR |
| Title | Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/s0074-02762012000600018 | |
| Abstract | Small non-coding RNAs derived from transfer RNAs have been identified as a broadly conserved prokaryotic and eukaryotic response to stress. Their presence coincides with changes in developmental state associated with gene expression regulation. In the epimastigote form of Trypanosoma cruzi, tRNA fragments localize to posterior cytoplasmic granules. In the infective metacyclic form of the parasite, we found tRNA-derived fragments to be abundant and evenly distributed within the cytoplasm. The fragments were not associated with polysomes, suggesting that the tRNA-derived fragments may not be directly involved in translation control in metacyclics. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil / Universidade Federal do Paraná. Setor de Ciências Biológicas. Departamento de Patologia Básica. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Institut Pasteur de Montevideo. Functional Genomics Unit. Mataojo, Montevideo, Uruguay. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Paraná. Setor de Ciências Biológicas. Departamento de Patologia Básica. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Institut Pasteur de Montevideo. Functional Genomics Unit. Mataojo, Montevideo, Uruguay. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | pt_BR |
| Subject | RNA Transfer | pt_BR |
| Subject | RNA Untranslated | pt_BR |
| Subject | Stress Physiological | pt_BR |
| Subject | Molecular Structure | pt_BR |
| Subject in Spanish | ARN de Transferencia | pt_BR |
| Subject in Spanish | ARN no Traducido | pt_BR |
| Subject in Spanish | Estrés Fisiológico | pt_BR |
| Subject in Spanish | Estructura Molecular | pt_BR |
| DeCS | RNA de Transferência | pt_BR |
| DeCS | RNA não Traduzido | pt_BR |
| DeCS | Estresse Fisiológico | pt_BR |
| DeCS | Estrutura Molecular | pt_BR |
| e-ISSN | 1678-8060 | |
