| Author | Gräf, Tiago | |
| Author | Delatorre, Edson | |
| Author | Bello, Gonzalo | |
| Access date | 2020-03-20T18:10:38Z | |
| Available date | 2020-03-20T18:10:38Z | |
| Document date | 2020 | |
| Citation | GRÄF, Tiago; DELATORRE, Edson; BELLO, Gonzalo. Phylogenetics applied to the human immunodeficiency virus type 1 (HIV-1): from the cross-species transmissions to the contact network inferences. Memórias do Instituto Oswaldo Cruz, v. 115, n. e190461, p. 1-5, 2020. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/40431 | |
| Sponsorship | CNPq | pt_BR |
| Sponsorship | FAPERJ | pt_BR |
| Language | eng | pt_BR |
| Publisher | Instituto Oswaldo Cruz, Ministério da Saúde | pt_BR |
| Rights | open access | |
| Subject in Portuguese | HIV-1 | pt_BR |
| Subject in Portuguese | Filogenética | pt_BR |
| Subject in Portuguese | Filogeografia | pt_BR |
| Subject in Portuguese | Clusters de transmissão | pt_BR |
| Title | Phylogenetics applied to the human immunodeficiency virus type 1 (HIV-1): from the cross-species transmissions to the contact network inferences | en_US |
| Type | Article | |
| DOI | 10.1590/0074-02760190461 | pt_BR |
| Abstract | Phylogenetic analyses were crucial to elucidate the origin and spread of the pandemic human immunodeficiency virus type 1 (HIV-1) group M virus, both during the pre-epidemic period of cryptic dissemination in human populations as well as during the epidemic phase of spread. The use of phylogenetics and phylodynamics approaches has provided important insights to track the founder events that resulted in the spread of HIV-1 strains across vast geographic areas, specific countries and within geographically restricted communities. In the recent years, the use of phylogenetic analysis combined with the huge availability of HIV sequences has become an increasingly important approach to reconstruct HIV transmission networks and understand transmission dynamics in concentrated and generalised epidemics. Significant efforts to obtain viral sequences from newly HIV-infected individuals could certainly contribute to detect rapidly expanding HIV-1 lineages, identify key populations at high-risk and understand what public health interventions should be prioritised in different scenarios. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Espírito Santo. Centro de Ciências Exatas, Naturais e da Saúde. Departamento de Biologia. Alegre, ES, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | HIV-1 | en_US |
| Subject | Phylogenetics | en_US |
| Subject | Phylogeography | en_US |
| Subject | Transmission clusters | en_US |
| e-ISSN | 1678-8060 | pt_BR |
