| Author | Melo, Raíssa de Fátima Pimentel | |
| Author | Guarneri, Alessandra Aparecida | |
| Author | Silber, Ariel Mariano | |
| Access date | 2020-04-28T14:01:32Z | |
| Available date | 2020-04-28T14:01:32Z | |
| Document date | 2020 | |
| Citation | MELO, Raíssa de Fátima Pimentel; GUARNERI, Alessandra Aparecida; SILBER, Ariel Mariano. The Influence of Environmental Cues on the Development of Trypanosoma cruzi in Triatominae Vector. Front Cell Infect Microbiol, v. 10, 27, 2020. | pt_BR |
| ISSN | 2235-2988 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/41005 | |
| Language | eng | pt_BR |
| Publisher | Frontiers Media | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Doença de chagas | pt_BR |
| Title | The Influence of Environmental Cues on the Development of Trypanosoma cruzi in Triatominae Vector | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.3389/fcimb.2020.00027 | |
| Abstract | Trypanosoma cruzi, a hemoflagellate parasite, is the etiological agent of Chagas disease that affects about 6-7 million people worldwide, mostly in Latin America. The parasite life cycle is complex and alternates between an invertebrate host-Triatominae vector-and a mammalian host. The parasite adaptation to the several microenvironments through which it transits is critical to success in establishing infection. Moreover, environmental cues also play an important role on the parasite development, and it can modulate the infection. In the present study, we discussed how the temperature oscillations and the nutritional state of the invertebrate host can affect the parasite development, multiplication, and the differentiation process of epimastigote forms into metacyclic trypomastigotes, called metacyclogenesis. The impact of oxidative imbalance and osmotic stresses on the parasite-vector relationship are also discussed. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Parasitologia. Laboratório de Bioquímica de Tryps. São Paulo, SP, Brazil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Grupo Comportamento vetorial e interação com Patógenos . Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Parasitologia. Laboratório de Bioquímica de Tryps. São Paulo, SP, Brazil | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| Subject | Chagas disease | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
