| Autor | Martins, Maria Auxiliadora | |
| Autor | Teixeira, Gil Cezar Alkmin | |
| Autor | Viana, Jaciara Machado | |
| Autor | Nicolini, Edson Antonio | |
| Autor | Martins Filho, Olindo Assis | |
| Autor | Rodrigues, Fernando Bellissimo | |
| Autor | Carlotti Junior, Carlos Gilberto | |
| Autor | Basile Filho, Aníbal | |
| Data de acesso | 2012-07-19T14:04:32Z | |
| Data de disponibilização | 2012-07-19T14:04:32Z | |
| Data do publicação | 2010 | |
| Citação | MARTINS, Maria Auxiliadora; et al. Meningoencephalitis caused by a zygomycete fungus (Basidiobolus) associated with septic shock in an immunocompetent patient: 1-year follow-up after treatment. Brazilian Journal of Medical and Biological Research (2010) 43: 794-798 | pt_BR |
| ISSN | 0100-879X | |
| URI | https://www.arca.fiocruz.br/handle/icict/4203 | |
| Idioma | eng | pt_BR |
| xmlui.metadata.dc.relation.ispartofseries | 43 | pt_BR |
| Direito Autoral | open access | pt_BR |
| Título | Meningoencephalitis caused by a zygomycete fungus (Basidiobolus) associated with septic shock in an immunocompetent patient: 1-year follow-up after treatment | pt_BR |
| Tipo do documento | Article | pt_BR |
| Grau | Brazilian Journal of Medical and Biological Research | pt_BR |
| Resumo em Inglês | Zygomycosis is an infection caused by opportunistic fungi of the Zygomycetes class, specifically those from the Mucorales and Entomophthorales orders. It is an uncommon disease, mainly restricted to immunocompromised patients. We report a case of a 73-year-old male patient with a history of fever (39°C) lasting for 1 day, accompanied by shivering, trembling, and intense asthenia. The patient was admitted to the intensive care unit with complex partial seizures, and submitted to orotracheal intubation and mechanical ventilation under sedation with midazolam. The electroencephalogram showed evidence of non-convulsive status epilepticus. There is no fast specific laboratory test that permits confirmation of invasive fungal disease. Unless the physician suspects this condition, the disease may progress rapidly while the patient is treated with broad-spectrum antibiotics. Differential diagnosis between fungal and bacterial infection is often difficult. The clinical presentation is sometimes atypical, and etiological investigation is not always successful. In the present case, the histopathological examination of the biopsy obtained from the right temporal lobe indicated the presence of irregular, round, thick-walled fungi forming papillae and elongated structures of irregular diameter, with no septa, indicative of zygomycete (Basidiobolus). Treatment with liposomal amphotericin B and fluconazole was initiated after diagnosis of meningoencephalitis by zygomycete, with a successful outcome. | pt_BR |
| Afiliação | Divisão de Terapia Intensiva, Departamento de Cirurgia e Anatomia | pt_BR |
| Afiliação | Divisão de Terapia Intensiva, Departamento de Cirurgia e Anatomia.Ribeirão Preto, SP, Brasil | pt_BR |
| Afiliação | Divisão de Terapia Intensiva, Departamento de Cirurgia e Anatomia.Ribeirão Preto, SP, Brasil | pt_BR |
| Afiliação | Divisão de Terapia Intensiva, Departamento de Cirurgia e Anatomia.Ribeirão Preto, SP, Brasil | pt_BR |
| Afiliação | Fundação Oswaldo Cruz . Centro de Pesquisas René Rachou. Laboratório de Biomarcadores de Diagnóstico e Monitoração. Belo Horizonte, MG, Brasil | pt_BR |
| Afiliação | Universidade de São Paulo . Faculdade de Medicina de Ribeirão Preto. Departamento de Medicina Social , Ribeirão Preto, SP, Brasil | pt_BR |
| Afiliação | Divisão de Neurocirurgia, Departamento de Cirurgia e Anatomia, Hospital das Clínicas.Ribeirão Preto, SP, Brasil | pt_BR |
| Afiliação | Divisão de Terapia Intensiva, Departamento de Cirurgia e Anatomia | pt_BR |
| Palavras-chave em inglês | Zygomycete | pt_BR |
| Palavras-chave em inglês | Septic shock | pt_BR |
| Palavras-chave em inglês | Status epilepticus | pt_BR |
| Palavras-chave em inglês | Meningoencephalitis | pt_BR |
| Palavras-chave em inglês | ICU setting | pt_BR |
