| Author | Colnago, Luiz Alberto | |
| Author | Trevisol, Iara Maria | |
| Author | Rech, Daiane Voss | |
| Author | Forato, Lucimara Aparecida | |
| Author | Mitre, Cirlei Igreja do Nascimento | |
| Author | Leite, José Paulo Gagliardi | |
| Author | Giglioti, Rodrigo | |
| Author | Okino, Cintia Hiromi | |
| Access date | 2020-09-11T20:25:22Z | |
| Available date | 2020-09-11T20:25:22Z | |
| Document date | 2020 | |
| Citation | COLNAGO, Luiz Alberto et al. Simple, Low-Cost and Long-Lasting Film for Virus Inactivation Using Avian Coronavirus Model as Challenge. International Journal of Environmental Research and Public Health. v. 17, n. 18, p. 1-9, Sept. 2020. | pt_BR |
| ISSN | 1661-7827 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/43340 | |
| Language | eng | pt_BR |
| Publisher | MDPI | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Coronavírus | pt_BR |
| Subject in Portuguese | Filme | pt_BR |
| Subject in Portuguese | Detergente | pt_BR |
| Subject in Portuguese | Antiviral | pt_BR |
| Subject in Portuguese | Virucida | pt_BR |
| Subject in Portuguese | Inativação | pt_BR |
| Subject in Portuguese | Sanitização | pt_BR |
| Subject in Portuguese | COVID-19 | pt_BR |
| Subject in Portuguese | SARS-CoV-2 | pt_BR |
| Title | Simple, Low-Cost and Long-Lasting Film for Virus Inactivation Using Avian Coronavirus Model as Challeng | pt_BR |
| Type | Article | |
| DOI | 10.3390/ijerph17186456 | |
| Abstract | The COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal among populations with lower socioeconomic status. Direct contact with contaminated surfaces has been among the virus sources, as it remains infective up to days. Several disinfectants have been shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare, low-cost and efficient antiviral films, made with a widely available dishwashing detergent, which can be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to test the antivirus efficacy of the proposed films. Polystyrene petri dishes were covered with a thin layer of detergent formula. After drying, the films were exposed to different virus doses for 10 min and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 103.7 to 106.7 EID50), which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent alternative to minimize the spread of COVID-19. | pt_BR |
| Affilliation | Embrapa Instrumentação. São Carlos, SP, Brasil. | pt_BR |
| Affilliation | Embrapa Suínos e Aves, Concórdia, SC, Brasil. | pt_BR |
| Affilliation | Embrapa Suínos e Aves, Concórdia, SC, Brasil. | pt_BR |
| Affilliation | Embrapa Instrumentação. São Carlos, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Química de São Carlos. São Carlos, SP, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Instituto de Zootecnia-IZ. Centro de Pesquisa de Genética e Reprodução Animal. Nova Odessa, SP, Brasil. | pt_BR |
| Affilliation | Embrapa Pecuária Sudeste. São Carlos, SP, Brasil. | pt_BR |
| Subject | Coronavirus | pt_BR |
| Subject | Film | pt_BR |
| Subject | Detergent | pt_BR |
| Subject | Antiviral | pt_BR |
| Subject | Virucide | pt_BR |
| Subject | Inactivation | pt_BR |
| Subject | Sanitization | pt_BR |
| Subject | COVID-19 | pt_BR |
| Subject | SARS-CoV-2 | pt_BR |
| e-ISSN | 1660-4601 | |
